Gene Symbol | WNT8B |
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Entrez Gene | 7479 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | wingless-type MMTV integration site family, member 8B |
Other Description | protein Wnt-8b |
Swissprots | Q8WYK9 Q5VX55 O00771 Q93098 |
Accessions | CAA71994 CAI38651 EAW49825 Q93098 AB073637 BAB83924 BC156632 AAI56633 CN276452 X91940 CAA63017 Y11094 CAA71968 NM_003393 NP_003384 |
Function | Ligand for members of the frizzled family of seven transmembrane receptors. May play an important role in the development and differentiation of certain forebrain structures, notably the hippocampus. {ECO:0000269|PubMed:9536085}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix. |
Tissue Specificity | Expression is restricted to the brain, and more specifically to the forebrain. {ECO:0000269|PubMed:9536085}. |
Top Pathways | Proteoglycans in cancer, Wnt signaling pathway, Signaling pathways regulating pluripotency of stem cells, Hippo signaling pathway, HTLV-I infection |
Wnt-8b CRISPR/Cas9 KO Plasmid (h) - sc-405077 from Santa Cruz Biotechnology
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Wnt-8b HDR Plasmid (h) - sc-405077-HDR from Santa Cruz Biotechnology
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Wnt-8b Double Nickase Plasmid (h) - sc-405077-NIC from Santa Cruz Biotechnology
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Wnt-8b Double Nickase Plasmid (h2) - sc-405077-NIC-2 from Santa Cruz Biotechnology
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Wnt-8b CRISPR Activation Plasmid (h) - sc-405077-ACT from Santa Cruz Biotechnology
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Wnt-8b CRISPR Activation Plasmid (h2) - sc-405077-ACT-2 from Santa Cruz Biotechnology
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Wnt-8b Lentiviral Activation Particles (h) - sc-405077-LAC from Santa Cruz Biotechnology
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Wnt-8b Lentiviral Activation Particles (h2) - sc-405077-LAC-2 from Santa Cruz Biotechnology
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Wnt-8b siRNA (h) - sc-41118 from Santa Cruz Biotechnology
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Wnt-8b shRNA Plasmid (h) - sc-41118-SH from Santa Cruz Biotechnology
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Wnt-8b shRNA (h) Lentiviral Particles - sc-41118-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN22926 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22926 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07161 from Sigma-Aldrich
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WNT8B siRNA (Human) - CRH5118 from Cohesion Biosciences
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WNT8B - MBS8235445 from MyBioSource
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shRNA set against Human WNT8B (NM_003393.3) - SHH447388 from Creative biogene
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WNT8B shRNA Plasmid (Human) - CHH5118 from Cohesion Biosciences
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WNT8B miRNA 3'UTR clone - MiUTR1H-11286 from Creative biogene
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