SIK2

Gene Symbol SIK2
Entrez Gene 23235
Alt Symbol LOH11CR1I, QIK, SIK-2, SNF1LK2
Species Human
Gene Type protein-coding
Description salt-inducible kinase 2
Other Description SNF1-like kinase 2|qin-induced kinase|salt-inducible protein kinase 2|salt-inducible serine/threonine kinase 2|serine/threonine-protein kinase SIK2|serine/threonine-protein kinase SNF1-like kinase 2
Swissprots Q9H0K1 Q6AZE2 O94878 B0YJ94 Q17RV0 A8K5B8 Q76N03 Q96CZ8 Q8NCV7
Accessions ACA06072 EAW67146 EAW67147 EAW67148 EAW67149 Q9H0K1 AB018324 BAA34501 AB084424 BAB91442 AB096248 AK000396 AK096463 AK291233 BAF83922 AL136764 CAB66698 BC013612 AAH13612 BC078150 AAH78150 BC113459 AAI13460 BC117183 AAI17184 BM799630 BM982514 BU621749 CB124295 DA333935 XM_011542716 XP_011541018 XM_011542717 XP_011541019 NM_015191 NP_056006
Function Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators. {ECO:0000269|PubMed:15454081}.
Subcellular Location Cytoplasm {ECO:0000250}.
Top Pathways Glucagon signaling pathway

SIK2 CRISPR/Cas9 KO Plasmid (h) - sc-406982 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SIK2 HDR Plasmid (h) - sc-406982-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SIK2 Double Nickase Plasmid (h) - sc-406982-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SIK2 Double Nickase Plasmid (h2) - sc-406982-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SIK2 CRISPR Activation Plasmid (h) - sc-406982-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SIK2 CRISPR Activation Plasmid (h2) - sc-406982-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SIK2 Lentiviral Activation Particles (h) - sc-406982-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SIK2 Lentiviral Activation Particles (h2) - sc-406982-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SIK2 siRNA (h) - sc-44364 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SIK2 shRNA Plasmid (h) - sc-44364-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SIK2 shRNA (h) Lentiviral Particles - sc-44364-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SNF1LK2/SIK2 RNAi - H00023235-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® siRNA - SIHK2097 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK2098 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

MISSION® siRNA - SIHK2099 from Sigma-Aldrich

Category siRNA
Prices $25.00
Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN19341 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19341 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SIK2 siRNA (Human) - CRH8110 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SIK2 - MBS8227551 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SIK2 (NM_015191.1) - SHH407536 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SNF1LK2(NM_015191.1) - SHR225668 from Creative biogene

Category siRNA
Species Reactivities Human

Human SIK2 siRNA - orb268612 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SIK2 shRNA Plasmid (Human) - CHH8110 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SIK2 miRNA 3'UTR clone - MiUTR1H-09690 from Creative biogene

Species Reactivities Human
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