SEMA4A

Gene Symbol SEMA4A
Entrez Gene 64218
Alt Symbol CORD10, RP35, SEMAB, SEMB
Species Human
Gene Type protein-coding
Description sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
Other Description sema B|semaphorin-4A|semaphorin-B
Swissprots Q5TCI5 Q9H3S1 Q8WUA9 B3KR76 Q5TCJ6 B2RDH8
Accessions EAW52992 EAW52993 EAW52994 EAW52995 Q9H3S1 AA761091 AB029394 BAB20087 AK022349 BAB14018 AK022416 AK091127 BAG52288 AK290353 BAF83042 AK296693 BAG59287 AK315547 BAG37925 AY358531 AAQ88895 BC020974 AAH20974 BX640891 CAE45942 DA409501 DA508826 DC332598 XM_011509871 XP_011508173 XM_011509872 XP_011508174 XM_011509873 XP_011508175 XM_011509874 XP_011508176 XM_011509875 XP_011508177 XM_011509876 XP_011508178 XM_011509877 XP_011508179 XM_011509878 XP_011508180 XM_011509879 XP_011508181 NM_001193300 NP_001180229 NM_001193301 NP_001180230 NM_001193302 NP_001180231 NM_022367 NP_071762
Function Cell surface receptor for PLXNB1, PLXNB2, PLXNB3 and PLXND1 that plays an important role in cell-cell signaling. Plays a role in priming antigen-specific T-cells, promotes differentiation of Th1 T-helper cells, and thereby contributes to adaptive immunity. Promotes phosphorylation of TIMD2. Inhibits angiogenesis. Promotes axon growth cone collapse. Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Top Pathways Axon guidance

Active human SEMA4A protein fragment - ab182683 from Abcam

Category Protein
Prices $372.00
Sizes 100 µg
Source HEK 293 cells
Species Human
SDS-PAGE analysis of reduced ab182683 stained overnight with Coomassie Blue.

Human SEMA4A full length protein - ab153481 from Abcam

Category Protein
Source Wheat germ
Species Human
ab153481 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human SEMA4A protein fragment - ab153482 from Abcam

Category Protein
Source Wheat germ
Species Human
ab153482 on a 12.5% SDS-PAGE stained with Coomassie Blue.

SEMA4A / Semaphorin 4A Antibody Blocking Peptide - LS-E4462 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

SEMA4A / Semaphorin 4A Antibody Blocking Peptide - LS-E11727 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human Semaphorin 4A Protein - H00064218-P01 from Novus Biologicals

Category Protein
Prices $319.00
Sizes 2 µg
Source Wheat Germ
Species Human

Semaphorin 4A Partial Recombinant Protein - H00064218-Q01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

SEMA4A-Antibody-N-term-Blocking-Peptide - BP16778a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Recombinant Human Semaphorin 4A Fc Chimera, CF - 4694-S4-050 from R&D Systems

Category Protein
Source Mouse myeloma cell line, NS0-derived

Human CORD10 protein - orb84136 from Biorbyt

Category Protein
Prices $400.00, $612.00
Sizes 50 μg, 100 μg
Source Human
Species Human
SDS-PAGE analysis of Human SEMA4A His tag protein

Human CORD10 protein - orb84309 from Biorbyt

Category Protein
Prices $400.00, $612.00
Sizes 50 μg, 100 μg
Source Human
Species Human
SDS-PAGE analysis of Human SEMA4A Fc tag protein

SEMA4A - H00064218-P01-10 from Acris Antibodies

Category Protein
Prices $370.00
Sizes 10 µg
Species Human

SEMA4A - H00064218-P01-25 from Acris Antibodies

Category Protein
Prices $520.00
Sizes 25 µg
Species Human

SEMA4A - H00064218-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

SEMA4A - H00064218-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

Semaphorin 4A Recombinant Protein - 96-686 from ProSci

Category Protein
Prices $375.00
Sizes 100 µg
Source HEK293 cells
Species Human
The purity of rh SEMA4A / Semaphorin 4A was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue.

SEMA4A fusion protein - ag2981 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Recombinant Human SEMA4A, Fc tagged - SEMA4A-3925H from Creative Biomart

Category Protein
Source Human Cells
Species Human

Recombinant Human SEMA4A, His tagged - SEMA4A-3926H from Creative Biomart

Category Protein
Source Human Cells
Species Human

Recombinant Semaphorin 4A (SEMA4A) - RPL921Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Human Semaphorin 4A / SEMA4A / Semaphorin B Protein (His Tag) - 11756-H08H-50 from Sino Biological

Category Protein
Prices $178.00, $298.00
Sizes 50 µg, 100 µg
Source Human Cells
Species Human

Human Semaphorin 4A / SEMA4A / Semaphorin B Protein (Fc Tag) - 11756-H02H-50 from Sino Biological

Category Protein
Prices $178.00, $298.00
Sizes 50 µg, 100 µg
Source Human Cells
Species Human

Semaphorin 4A Blocking Peptide - CBP2752 from Cohesion Biosciences

Category Peptide
Prices $100.00, $300.00
Sizes 1 mg, 5 mg
Species Human, Monkey

SEMA4A (N532) Peptide - BS2363P from Bioworld Technology

Category Peptide
Prices $158.00
Sizes 100 µl
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