SLC3A1

Gene Symbol	SLC3A1
Entrez Gene	6519
Alt Symbol	ATR1, CSNU1, D2H, NBAT, RBAT
Species	Human
Gene Type	protein-coding
Description	solute carrier family 3 (amino acid transporter heavy chain), member 1
Other Description	B(0,+)-type amino acid transport protein|SLC3A1 variant B|SLC3A1 variant C|SLC3A1 variant D|SLC3A1 variant E|SLC3A1 variant F|SLC3A1 variant G|amino acid transporter 1|neutral and basic amino acid transport protein rBAT|solute carrier family 3 (cystine, dibasic and neutral amino acid transporters), member 1|solute carrier family 3 (cystine, dibasic and neutral amino acid transporters, activator of cystine, dibasic and neutral amino acid transport), member 1|solute carrier family 3 member 1
Swissprots	Q4J6B6 Q07837 Q52M92 Q15295 Q52M94 Q4J6B7 O00658 Q4J6B5 Q4J6B9 A8K0S1 Q4J6B8 Q4J6B4
Accessions	AAB39829 AAX88955 EAX00278 EAX00279 Q07837 AB033549 BAB16841 AK091932 BAG52443 AK092000 AK223146 BAD96866 AK289636 BAF82325 AK309145 AK313157 BAG35975 BC022386 AAH22386 BC093624 AAH93624 BC093626 AAH93626 DQ023512 AAY89643 DQ023513 AAY89644 DQ023514 AAY89645 DQ023515 AAY89646 DQ023516 AAY89647 DQ023517 AAY89648 DQ892031 ABM82957 DQ895222 ABM86148 L11696 AAA81778 M95548 AAA35500 XM_011533047 XP_011531349 NM_000341 NP_000332
Function	Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system B(0,+)-like activity). May function as an activator of SLC7A9 and be involved in the high-affinity reabsorption of cystine in the kidney tubule. {ECO:0000269|PubMed:11318953, ECO:0000269|PubMed:7686906, ECO:0000269|PubMed:8486766, ECO:0000269|PubMed:8663184}.
Subcellular Location	Membrane {ECO:0000269|PubMed:12167606}; Single-pass type II membrane protein {ECO:0000269|PubMed:12167606}.
Tissue Specificity	Expressed in the brush border membrane in the kidney (at protein level). Predominantly expressed in the kidney, small intestine and pancreas. Weakly expressed in liver. {ECO:0000269|PubMed:12167606, ECO:0000269|PubMed:7686906, ECO:0000269|PubMed:8486766}.
Top Pathways	Protein digestion and absorption

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

rBAT (C-10) - sc-393589 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

rBAT (N-20) - sc-27597 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

rBAT (H-300) - sc-32930 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Anti-SLC3A1 antibody - ab196552 from Abcam Prices $370.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-SLC3A1 antibody - ab58296 from Abcam Prices $370.00 Sizes 50 µg Host Mouse Clonality Monoclonal

Anti-SLC3A1 antibody - ab172120 from Abcam Prices $370.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-SLC3A1 / ATR1 Antibody - LS-C341643 from LifeSpan Bioscience Prices $385.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-SLC3A1 / ATR1 Antibody (aa179-228) - LS-C110813 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-SLC3A1 / ATR1 Antibody (clone 3G3) - LS-C139468 from LifeSpan Bioscience Prices $355.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 3G3

Anti-SLC3A1 / ATR1 Antibody (aa163-192) - LS-C161246 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-SLC3A1 / ATR1 Antibody - LS-C179210 from LifeSpan Bioscience Prices $365.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-SLC3A1 / ATR1 Antibody - LS-C334095 from LifeSpan Bioscience Prices $255.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-SLC3A1 / ATR1 Antibody (Internal, AP) - LS-C220734 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SLC3A1 / ATR1 Antibody (Internal, APC) - LS-C220733 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SLC3A1 / ATR1 Antibody (Internal, Biotin) - LS-C220735 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SLC3A1 / ATR1 Antibody (Internal, FITC) - LS-C220736 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SLC3A1 / ATR1 Antibody (Internal, Azide-free, HRP) - LS-C220737 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SLC3A1 / ATR1 Antibody (aa60-427) - LS-C311599 from LifeSpan Bioscience Prices $250.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-SLC3A1 / ATR1 Antibody (Internal, PE) - LS-C220738 from LifeSpan Bioscience Prices $515.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-SLC3A1 / ATR1 Antibody (Internal) - LS-C330662 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

SLC3A1 Antibody - NBP1-59700 from Novus Biologicals Prices $369.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

SLC3A1 Antibody (2F2) - H00006519-M01A from Novus Biologicals Prices $349.00 Sizes 200 µl Host Mouse Clonality Monoclonal Clone 2F2

SLC3A1 Antibody (2F2) - H00006519-M01 from Novus Biologicals Host Mouse Clonality Monoclonal Clone 2F2

SLC3A1 Antibody (3G3) - H00006519-M02 from Novus Biologicals Prices $349.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 3G3

SLC3A1 Antibody - H00006519-A01 from Novus Biologicals Prices $269.00 Sizes 50 µl Host Mouse Clonality Polyclonal

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