SLC3A1

Gene Symbol SLC3A1
Entrez Gene 6519
Alt Symbol ATR1, CSNU1, D2H, NBAT, RBAT
Species Human
Gene Type protein-coding
Description solute carrier family 3 (amino acid transporter heavy chain), member 1
Other Description B(0,+)-type amino acid transport protein|SLC3A1 variant B|SLC3A1 variant C|SLC3A1 variant D|SLC3A1 variant E|SLC3A1 variant F|SLC3A1 variant G|amino acid transporter 1|neutral and basic amino acid transport protein rBAT|solute carrier family 3 (cystine, dibasic and neutral amino acid transporters), member 1|solute carrier family 3 (cystine, dibasic and neutral amino acid transporters, activator of cystine, dibasic and neutral amino acid transport), member 1|solute carrier family 3 member 1
Swissprots Q4J6B6 Q07837 Q52M92 Q15295 Q52M94 Q4J6B7 O00658 Q4J6B5 Q4J6B9 A8K0S1 Q4J6B8 Q4J6B4
Accessions AAB39829 AAX88955 EAX00278 EAX00279 Q07837 AB033549 BAB16841 AK091932 BAG52443 AK092000 AK223146 BAD96866 AK289636 BAF82325 AK309145 AK313157 BAG35975 BC022386 AAH22386 BC093624 AAH93624 BC093626 AAH93626 DQ023512 AAY89643 DQ023513 AAY89644 DQ023514 AAY89645 DQ023515 AAY89646 DQ023516 AAY89647 DQ023517 AAY89648 DQ892031 ABM82957 DQ895222 ABM86148 L11696 AAA81778 M95548 AAA35500 XM_011533047 XP_011531349 NM_000341 NP_000332
Function Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system B(0,+)-like activity). May function as an activator of SLC7A9 and be involved in the high-affinity reabsorption of cystine in the kidney tubule. {ECO:0000269|PubMed:11318953, ECO:0000269|PubMed:7686906, ECO:0000269|PubMed:8486766, ECO:0000269|PubMed:8663184}.
Subcellular Location Membrane {ECO:0000269|PubMed:12167606}; Single-pass type II membrane protein {ECO:0000269|PubMed:12167606}.
Tissue Specificity Expressed in the brush border membrane in the kidney (at protein level). Predominantly expressed in the kidney, small intestine and pancreas. Weakly expressed in liver. {ECO:0000269|PubMed:12167606, ECO:0000269|PubMed:7686906, ECO:0000269|PubMed:8486766}.
Top Pathways Protein digestion and absorption

rBAT CRISPR/Cas9 KO Plasmid (h) - sc-405282 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

rBAT HDR Plasmid (h) - sc-405282-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

rBAT Double Nickase Plasmid (h) - sc-405282-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

rBAT Double Nickase Plasmid (h2) - sc-405282-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

rBAT CRISPR Activation Plasmid (h) - sc-405282-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

rBAT CRISPR Activation Plasmid (h2) - sc-405282-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

rBAT Lentiviral Activation Particles (h) - sc-405282-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

rBAT Lentiviral Activation Particles (h2) - sc-405282-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

rBAT siRNA (h) - sc-106486 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

rBAT shRNA Plasmid (h) - sc-106486-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

rBAT shRNA (h) Lentiviral Particles - sc-106486-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SLC3A1 RNAi - H00006519-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU110111 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19628 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19628 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01494 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01494

SLC3A1 siRNA (Human) - CRH4413 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC3A1 - MBS8201425 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human SLC3A1 siRNA - orb264915 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLC3A1 shRNA Plasmid (Human) - CHH4413 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SLC3A1 miRNA 3'UTR clone - MiUTR4H-TG08110 from Creative biogene

Species Reactivities Human
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