| Gene Symbol |
CTNNA3
|
| Entrez Gene |
29119
|
| Alt Symbol |
ARVD13, VR22
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
catenin (cadherin-associated protein), alpha 3
|
| Other Description |
alpha-T-catenin|alpha-catenin-like protein|catenin alpha-3
|
| Swissprots |
Q5VSR2 Q9UI47 Q6P056
|
| Accessions |
AAQ14328 CCQ43416 EAW54249 EAW54250 EAW54251 Q9UI47 AF091606 AAF21801 AK289756 BAF82445 AK308726 AK313882 BAG36608 AY198183 AAO43101 BC022004 AAH22004 BC030646 AAH30646 BC065819 AAH65819 BP362015 BX103986 XM_005269717 XP_005269774 XM_011539721 XP_011538023 XM_011539722 XP_011538024 XM_011539723 XP_011538025 XM_011539724 XP_011538026 XM_011539725 XP_011538027 XM_011539726 XP_011538028 XM_011539727 XP_011538029 NM_001127384 NP_001120856 NM_001291133 NP_001278062 NM_013266 NP_037398
|
| Function |
May be involved in formation of stretch-resistant cell- cell adhesion complexes. {ECO:0000303|PubMed:11590244}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000305}. Note=Localizes to intercalated disks of cardiomyocytes and in peritubular myoid cells of testis, and colocalizes with CTNNA1 and CTNNA2. {ECO:0000269|PubMed:11590244}.
|
| Tissue Specificity |
Predominantly expressed in heart and testis. Expressed at lower levels in brain, kidney, liver and skeletal muscle. {ECO:0000269|PubMed:11590244}.
|
| Top Pathways |
Adherens junction, Tight junction, Leukocyte transendothelial migration, Endometrial cancer, Arrhythmogenic right ventricular cardiomyopathy (ARVC)
|
![Western Blot: CTNNA3 Overexpression Lysate (Adult Normal) [NBP2-07428] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CTNNA3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6213_CTNNA3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07428-img0001.jpg)