| Gene Symbol |
CXCR3
|
| Entrez Gene |
2833
|
| Alt Symbol |
CD182, CD183, CKR-L2, CMKAR3, GPR9, IP10-R, Mig-R, MigR
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
chemokine (C-X-C motif) receptor 3
|
| Other Description |
C-X-C chemokine receptor type 3|CXC-R3|CXCR-3|G protein-coupled receptor 9|IP-10 receptor|IP10 receptor|Mig receptor|chemokine (C-X-C) receptor 3|interferon-inducible protein 10 receptor
|
| Swissprots |
P49682 Q9P2T5 Q7Z710 O15185 B2R982 Q9P2T4
|
| Accessions |
AAC50505 BAA92297 BAA92298 BAA92299 BAA92300 CAB02143 CAH05336 CBX47662 EAX05283 P49682 AF469635 AAP55851 AK313679 BAG36429 AY242128 AAO92295 BC034403 AAH34403 DQ892460 ABM83386 DQ895673 ABM86599 X95876 CAA65126 XM_005262256 XP_005262313 XM_005262257 XP_005262314 NM_001142797 NP_001136269 NM_001504 NP_001495
|
| Function |
Isoform 3: Mediates the activity of CXCL11.
|
| Subcellular Location |
Isoform 1: Cell membrane {ECO:0000269|PubMed:12782716}; Multi-pass membrane protein {ECO:0000269|PubMed:12782716}.
|
| Tissue Specificity |
Isoform 1 and isoform 2 are mainly expressed in heart, kidney, liver and skeletal muscle. Isoform 1 is also expressed in placenta. Isoform 2 is expressed in endothelial cells. Expressed in T-cells (at protein level). {ECO:0000269|PubMed:12782716, ECO:0000269|PubMed:23121557}.
|
| Top Pathways |
Cytokine-cytokine receptor interaction, Chemokine signaling pathway
|
![Western Blot: CXCR3 Overexpression Lysate (Adult Normal) [NBL1-09631] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for CXCR3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8076_CXCR3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-09631-img0002.jpg)