Gene Symbol | CXCR3 |
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Entrez Gene | 2833 |
Alt Symbol | CD182, CD183, CKR-L2, CMKAR3, GPR9, IP10-R, Mig-R, MigR |
Species | Human |
Gene Type | protein-coding |
Description | chemokine (C-X-C motif) receptor 3 |
Other Description | C-X-C chemokine receptor type 3|CXC-R3|CXCR-3|G protein-coupled receptor 9|IP-10 receptor|IP10 receptor|Mig receptor|chemokine (C-X-C) receptor 3|interferon-inducible protein 10 receptor |
Swissprots | P49682 Q9P2T5 Q7Z710 O15185 B2R982 Q9P2T4 |
Accessions | AAC50505 BAA92297 BAA92298 BAA92299 BAA92300 CAB02143 CAH05336 CBX47662 EAX05283 P49682 AF469635 AAP55851 AK313679 BAG36429 AY242128 AAO92295 BC034403 AAH34403 DQ892460 ABM83386 DQ895673 ABM86599 X95876 CAA65126 XM_005262256 XP_005262313 XM_005262257 XP_005262314 NM_001142797 NP_001136269 NM_001504 NP_001495 |
Function | Isoform 3: Mediates the activity of CXCL11. |
Subcellular Location | Isoform 1: Cell membrane {ECO:0000269|PubMed:12782716}; Multi-pass membrane protein {ECO:0000269|PubMed:12782716}. |
Tissue Specificity | Isoform 1 and isoform 2 are mainly expressed in heart, kidney, liver and skeletal muscle. Isoform 1 is also expressed in placenta. Isoform 2 is expressed in endothelial cells. Expressed in T-cells (at protein level). {ECO:0000269|PubMed:12782716, ECO:0000269|PubMed:23121557}. |
Top Pathways | Cytokine-cytokine receptor interaction, Chemokine signaling pathway |
CXCR-3 CRISPR/Cas9 KO Plasmid (h) - sc-401933 from Santa Cruz Biotechnology
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CXCR-3 HDR Plasmid (h) - sc-401933-HDR from Santa Cruz Biotechnology
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CXCR-3 Double Nickase Plasmid (h) - sc-401933-NIC from Santa Cruz Biotechnology
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CXCR-3 Double Nickase Plasmid (h2) - sc-401933-NIC-2 from Santa Cruz Biotechnology
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CXCR-3 CRISPR Activation Plasmid (h) - sc-401933-ACT from Santa Cruz Biotechnology
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CXCR-3 CRISPR Activation Plasmid (h2) - sc-401933-ACT-2 from Santa Cruz Biotechnology
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CXCR-3 Lentiviral Activation Particles (h) - sc-401933-LAC from Santa Cruz Biotechnology
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CXCR-3 Lentiviral Activation Particles (h2) - sc-401933-LAC-2 from Santa Cruz Biotechnology
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CXCR-3 siRNA (h) - sc-39902 from Santa Cruz Biotechnology
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CXCR-3 shRNA Plasmid (h) - sc-39902-SH from Santa Cruz Biotechnology
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CXCR-3 shRNA (h) Lentiviral Particles - sc-39902-V from Santa Cruz Biotechnology
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CXCR3 RNAi - H00002833-R02 from Novus Biologicals
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MISSION® esiRNA - EHU150831 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6812 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6812 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03700 from Sigma-Aldrich
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CXCR3 siRNA (Human) - CRH1898 from Cohesion Biosciences
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CXCR3 - MBS828305 from MyBioSource
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shRNA set against Human CXCR3 (NM_001504.1) - SHH272273 from Creative biogene
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shRNA set against Human CXCR3(NM_001504.1) - SHG213217 from Creative biogene
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Human CXCR3 siRNA - orb262400 from Biorbyt
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CXCR3 shRNA Plasmid (Human) - CHH1898 from Cohesion Biosciences
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CXCR3 miRNA 3'UTR clone - MiUTR1H-02577 from Creative biogene
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CXCR3 miRNA 3'UTR clone - MiUTR3H-02856 from Creative biogene
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