| Gene Symbol |
St6galnac5
|
| Entrez Gene |
26938
|
| Alt Symbol |
AI851940, Siat7e
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
|
| Other Description |
GD1 alpha synthase|SIAT7-E|ST6GalNAc V|ST6GalNAcV|alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5|galNAc alpha-2,6-sialyltransferase V|sialyltransferase 7 ((alpha-N-acetylneuraminyl 2,3-betagalactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase) E|sialyltransferase 7E
|
| Swissprots |
Q9QYJ1 Q9R0K6
|
| Accessions |
EDL11913 Q9QYJ1 AB028840 BAA89292 AB030836 BAA85747 AK034387 BAC28693 AK038434 BAC29997 AK042683 BAC31331 BC055737 AAH55737 NM_012028 NP_036158
|
| Function |
Involved in the biosynthesis of ganglioside GD1a from GM1b. It exhibits higher activity with glycolipids than with glycoproteins. {ECO:0000269|PubMed:10521438, ECO:0000269|PubMed:10601645}.
|
| Subcellular Location |
Golgi apparatus membrane; Single-pass type II membrane protein.
|
| Tissue Specificity |
High expression in forebrain and to a lesser extent in cerebellum. No expression in salivary gland, intestine, liver, kidney, heart, lung, thymus and spleen. {ECO:0000269|PubMed:10521438, ECO:0000269|PubMed:10601645}.
|
| Top Pathways |
Glycosphingolipid biosynthesis - ganglio series
|