Gene Symbol | St6galnac5 |
---|---|
Entrez Gene | 26938 |
Alt Symbol | AI851940, Siat7e |
Species | Mouse |
Gene Type | protein-coding |
Description | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 |
Other Description | GD1 alpha synthase|SIAT7-E|ST6GalNAc V|ST6GalNAcV|alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5|galNAc alpha-2,6-sialyltransferase V|sialyltransferase 7 ((alpha-N-acetylneuraminyl 2,3-betagalactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase) E|sialyltransferase 7E |
Swissprots | Q9QYJ1 Q9R0K6 |
Accessions | EDL11913 Q9QYJ1 AB028840 BAA89292 AB030836 BAA85747 AK034387 BAC28693 AK038434 BAC29997 AK042683 BAC31331 BC055737 AAH55737 NM_012028 NP_036158 |
Function | Involved in the biosynthesis of ganglioside GD1a from GM1b. It exhibits higher activity with glycolipids than with glycoproteins. {ECO:0000269|PubMed:10521438, ECO:0000269|PubMed:10601645}. |
Subcellular Location | Golgi apparatus membrane; Single-pass type II membrane protein. |
Tissue Specificity | High expression in forebrain and to a lesser extent in cerebellum. No expression in salivary gland, intestine, liver, kidney, heart, lung, thymus and spleen. {ECO:0000269|PubMed:10521438, ECO:0000269|PubMed:10601645}. |
Top Pathways | Glycosphingolipid biosynthesis - ganglio series |
Sialyltransferase 7E CRISPR/Cas9 KO Plasmid (m) - sc-424149 from Santa Cruz Biotechnology
|
||||||||
Sialyltransferase 7E HDR Plasmid (m) - sc-424149-HDR from Santa Cruz Biotechnology
|
||||||||
Sialyltransferase 7E Double Nickase Plasmid (m) - sc-424149-NIC from Santa Cruz Biotechnology
|
||||||||
Sialyltransferase 7E Double Nickase Plasmid (m2) - sc-424149-NIC-2 from Santa Cruz Biotechnology
|
||||||||
Sialyltransferase 7E CRISPR Activation Plasmid (m) - sc-424149-ACT from Santa Cruz Biotechnology
|
||||||||
Sialyltransferase 7E CRISPR Activation Plasmid (m2) - sc-424149-ACT-2 from Santa Cruz Biotechnology
|
||||||||
Sialyltransferase 7E Lentiviral Activation Particles (m) - sc-424149-LAC from Santa Cruz Biotechnology
|
||||||||
Sialyltransferase 7E Lentiviral Activation Particles (m2) - sc-424149-LAC-2 from Santa Cruz Biotechnology
|
||||||||
Sialyltransferase 7E siRNA (m) - sc-72300 from Santa Cruz Biotechnology
|
||||||||
Sialyltransferase 7E shRNA Plasmid (m) - sc-72300-SH from Santa Cruz Biotechnology
|
||||||||
Sialyltransferase 7E shRNA (m) Lentiviral Particles - sc-72300-V from Santa Cruz Biotechnology
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN42129 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND42129 from Sigma-Aldrich
|
||||||||
ST6GALNAC5 siRNA (Mouse) - CRM4821 from Cohesion Biosciences
|
||||||||
ST6GALNAC5 - MBS8222454 from MyBioSource
|
||||||||
shRNA set against Mouse ST6GALNAC5 (NM_012028.4) - SHH418956 from Creative biogene
|
||||||||
shRNA set against Mouse St6galnac5(NM_012028.4) - SHL038710 from Creative biogene
|
||||||||
Mouse ST6GALNAC5 siRNA - orb284297 from Biorbyt
|
||||||||
ST6GALNAC5 shRNA Plasmid (Mouse) - CHM4821 from Cohesion Biosciences
|
||||||||
ST6GALNAC5 miRNA 3'UTR clone - MiUTR1M-11283 from Creative biogene
|