| Gene Symbol | St6galnac5 |
|---|---|
| Entrez Gene | 26938 |
| Alt Symbol | AI851940, Siat7e |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 |
| Other Description | GD1 alpha synthase|SIAT7-E|ST6GalNAc V|ST6GalNAcV|alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5|galNAc alpha-2,6-sialyltransferase V|sialyltransferase 7 ((alpha-N-acetylneuraminyl 2,3-betagalactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase) E|sialyltransferase 7E |
| Swissprots | Q9QYJ1 Q9R0K6 |
| Accessions | EDL11913 Q9QYJ1 AB028840 BAA89292 AB030836 BAA85747 AK034387 BAC28693 AK038434 BAC29997 AK042683 BAC31331 BC055737 AAH55737 NM_012028 NP_036158 |
| Function | Involved in the biosynthesis of ganglioside GD1a from GM1b. It exhibits higher activity with glycolipids than with glycoproteins. {ECO:0000269|PubMed:10521438, ECO:0000269|PubMed:10601645}. |
| Subcellular Location | Golgi apparatus membrane; Single-pass type II membrane protein. |
| Tissue Specificity | High expression in forebrain and to a lesser extent in cerebellum. No expression in salivary gland, intestine, liver, kidney, heart, lung, thymus and spleen. {ECO:0000269|PubMed:10521438, ECO:0000269|PubMed:10601645}. |
| Top Pathways | Glycosphingolipid biosynthesis - ganglio series |