Gene Symbol | USP47 |
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Entrez Gene | 55031 |
Alt Symbol | TRFP |
Species | Human |
Gene Type | protein-coding |
Description | ubiquitin specific peptidase 47 |
Other Description | Trf (TATA binding protein-related factor)-proximal homolog|deubiquitinating enzyme 47|ubiquitin carboxyl-terminal hydrolase 47|ubiquitin thioesterase 47|ubiquitin thiolesterase 47|ubiquitin-specific-processing protease 47 |
Swissprots | Q9BWI0 Q8TEP6 Q96K76 E9PM46 Q658U0 Q9NWN1 B3KXF5 Q86Y73 |
Accessions | EAW68542 EAW68543 EAW68544 Q96K76 AF059318 AAG43115 AI126428 AK000734 BAA91348 AK027283 AK027362 BAB55063 AK074076 BAB84902 AK092290 BAG52521 AK093714 AK127264 BAG54467 AK225358 AK309240 AL832991 CAH56337 BC000226 AAH00226 BC017795 AAH17795 BC030562 BC047044 AAH47044 BC071559 BC148587 AAI48588 BG752249 BM314303 DA490237 XM_005252997 XP_005253054 XM_011520196 XP_011518498 NM_001282659 NP_001269588 NM_017944 NP_060414 |
Function | Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER). Acts as a regulator of cell growth and genome integrity. May also indirectly regulates CDC25A expression at a transcriptional level. {ECO:0000269|PubMed:19966869, ECO:0000269|PubMed:21362556}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:21362556}. |
Tissue Specificity | Expressed in skeletal muscle, heart and testis. {ECO:0000269|PubMed:14715245}. |
USP47 (4E7) - sc-100633 from Santa Cruz Biotechnology
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USP47 (D-19) - sc-82402 from Santa Cruz Biotechnology
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USP47 (K-18) - sc-82403 from Santa Cruz Biotechnology
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Anti-USP47 antibody - ab101485 from Abcam
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Anti-USP47 antibody - ab72143 from Abcam
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Anti-USP47 antibody - ab97835 from Abcam
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Anti-USP47 antibody - ab57530 from Abcam
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Anti-USP47 Antibody - LS-C91887 from LifeSpan Bioscience
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Anti-USP47 Antibody (aa1-50) - LS-C287879 from LifeSpan Bioscience
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Anti-USP47 Antibody (aa203-302, Azide-free) - LS-C329078 from LifeSpan Bioscience
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Anti-USP47 Antibody (aa901-950) - LS-C135515 from LifeSpan Bioscience
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Anti-USP47 Antibody (C-Terminus) - LS-C287880 from LifeSpan Bioscience
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Anti-USP47 Antibody (aa635-870) - LS-C185775 from LifeSpan Bioscience
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Anti-USP47 Antibody (C-Terminus) - LS-C286483 from LifeSpan Bioscience
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USP47 Antibody - NB100-57487 from Novus Biologicals
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USP47 Antibody (5F9) - H00055031-M01 from Novus Biologicals
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USP47 Antibody - NBP1-85942 from Novus Biologicals
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USP47 Antibody - NBP2-20836 from Novus Biologicals
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USP47 Antibody - H00055031-A01 from Novus Biologicals
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Monoclonal Anti-USP47 antibody produced in mouse - WH0055031M1 from Sigma-Aldrich
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Anti-USP47 antibody produced in rabbit - HPA029289 from Sigma-Aldrich
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Monoclonal Anti-USP47 antibody produced in mouse - SAB1405138 from Sigma-Aldrich
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Anti-USP47 antibody produced in rabbit - HPA029286 from Sigma-Aldrich
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USP47 antibody - middle region (ARP59333_P050) - ARP59333_P050 from Aviva Systems Biology
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USP47-Antibody-monoclonal-M01 - AT4493a from Abgent, a WuXi AppTec company
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