Gene Symbol | USP47 |
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Entrez Gene | 55031 |
Alt Symbol | TRFP |
Species | Human |
Gene Type | protein-coding |
Description | ubiquitin specific peptidase 47 |
Other Description | Trf (TATA binding protein-related factor)-proximal homolog|deubiquitinating enzyme 47|ubiquitin carboxyl-terminal hydrolase 47|ubiquitin thioesterase 47|ubiquitin thiolesterase 47|ubiquitin-specific-processing protease 47 |
Swissprots | Q9BWI0 Q8TEP6 Q96K76 E9PM46 Q658U0 Q9NWN1 B3KXF5 Q86Y73 |
Accessions | EAW68542 EAW68543 EAW68544 Q96K76 AF059318 AAG43115 AI126428 AK000734 BAA91348 AK027283 AK027362 BAB55063 AK074076 BAB84902 AK092290 BAG52521 AK093714 AK127264 BAG54467 AK225358 AK309240 AL832991 CAH56337 BC000226 AAH00226 BC017795 AAH17795 BC030562 BC047044 AAH47044 BC071559 BC148587 AAI48588 BG752249 BM314303 DA490237 XM_005252997 XP_005253054 XM_011520196 XP_011518498 NM_001282659 NP_001269588 NM_017944 NP_060414 |
Function | Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER). Acts as a regulator of cell growth and genome integrity. May also indirectly regulates CDC25A expression at a transcriptional level. {ECO:0000269|PubMed:19966869, ECO:0000269|PubMed:21362556}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:21362556}. |
Tissue Specificity | Expressed in skeletal muscle, heart and testis. {ECO:0000269|PubMed:14715245}. |
Human USP47 full length protein - ab162936 from Abcam
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Human USP47 protein fragment - ab162937 from Abcam
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USP47 Antibody Blocking Peptide - LS-E21705 from LifeSpan Bioscience
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Recombinant Human USP47 Protein - H00055031-Q01 from Novus Biologicals
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Recombinant Human USP47 Protein - H00055031-P01 from Novus Biologicals
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USP47 Blocking Peptide - 33R-8539 from Fitzgerald
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USP47 - H00055031-P01-10 from Acris Antibodies
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USP47 - H00055031-P01-25 from Acris Antibodies
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USP47 - H00055031-Q01-10 from Acris Antibodies
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USP47 - H00055031-Q01-25 from Acris Antibodies
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USP47 fusion protein - ag13990 from Proteintech Group
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USP47 fusion protein - Ag16818 from Proteintech Group
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Recombinant Human USP47, His-tagged - USP47-157H from Creative Biomart
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Recombinant Human Ubiquitin carboxyl-terminal hydrolase 47(USP47) ,partial - CSB-YP856964HU CSB-EP856964HU CSB-BP856964HU CSB-MP856964HU from Cusabio
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Recombinant Human USP47 protein, GST-tagged - USP47-16H from Creative Biomart
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USP47 Recombinant Protein Antigen - NBP1-85942PEP from Novus Biologicals
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USP47 Recombinant Protein Antigen - NBP1-86362PEP from Novus Biologicals
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USP47-Blocking-Peptide-Center - BP21508c from Abgent, a WuXi AppTec company
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USP47 Peptide, Human - M34GP17190H from Creative Peptides
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