TRIM2

Gene Symbol TRIM2
Entrez Gene 23321
Alt Symbol CMT2R, RNF86
Species Human
Gene Type protein-coding
Description tripartite motif containing 2
Other Description E3 ubiquitin-protein ligase TRIM2|RING finger protein 86|tripartite motif protein TRIM2|tripartite motif-containing protein 2
Swissprots Q9BSI9 D3DP09 O60272 Q9UFZ1 Q9C040
Accessions CAX86997 CAY39311 EAX04960 EAX04961 EAX04962 EAX04963 Q9C040 AB011089 BAA25443 AF220018 AAG53472 AK000179 AK308731 AL110178 AL110234 CAB53687 AW071795 BC005016 AAH05016 BC011052 AAH11052 BC019242 BC025417 BP310511 CF529079 DA310963 DA407606 DA631098 JF432883 ADZ16100 XM_006714157 XP_006714220 XM_006714158 XP_006714221 XM_006714159 XP_006714222 XM_006714160 XP_006714223 XM_006714161 XP_006714224 XM_006714162 XP_006714225 XM_006714164 XP_006714227 XM_006714165 XP_006714228 XM_011531794 XP_011530096 XM_011531795 XP_011530097 XM_011531796 XP_011530098 XM_011531797 XP_011530099 XM_011531798 XP_011530100 XM_011531799 XP_011530101 NM_001130067 NP_001123539 NM_001302692 NP_001289621 NM_001302693 NP_001289622 NM_001302694 NP_001289623 NM_015271 NP_056086
Function UBE2D1-dependent E3 ubiquitin-protein ligase that mediates the ubiquitination of NEFL and of phosphorylated BCL2L11. Plays a neuroprotective function. May play a role in neuronal rapid ischemic tolerance. {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}.

TRIM2 (I-17) - sc-79161 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TRIM2 (I-17): sc-79161. Western blot analysis of TRIM2 expression in non-transfected: sc-117752 (A) and human TRIM2 transfected: sc-375136 (B) 293T whole cell lysates.

TRIM2 (N-17) - sc-79163 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TRIM2 (N-17): sc-79163. Western blot analysis of TRIM2 expression in non-transfected: sc-110760 (A) and human TRIM2 transfected: sc-375136 (B) whole cell lysates.

Anti-RNF86 antibody - ab3942 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-RNF86 antibody (ab3942) at 0.5 µg/ml + Tissue lysates prepared from Rat brain at 35 µgObserved band size : 80,85 kDa (why is the actual band size different from the predicted?)Additional bands at : 30 kDa. We are unsure as to the identity of these extra bands.

Anti-RNF86 antibody - ab115029 from Abcam

Prices $370.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-RNF86 antibody (ab115029) at 0.1 µg/ml + Mouse brain lysate (in RIPA buffer) at 35 µgdeveloped using the ECL technique

Anti-RNF86 antibody - ab124075 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-RNF86 antibody (ab124075) at 1/100 dilution + Human U251 cell line lysate at 35 µg

Anti-RNF86 antibody [4E5] - ab123899 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4E5
All lanes : Anti-RNF86 antibody [4E5] (ab123899) at 1/500 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY controlLane 2 : HEK293T cell lysate transfec ted with pCMV6-ENTRY RNF86 cDNALysates/proteins at 5 µg per lane.

Anti-KIAA0517 / TRIM2 Antibody (clone 2B2) - LS-C172356 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2B2
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TRIM2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TRIM2.

Anti-KIAA0517 / TRIM2 Antibody (clone 1D2) - LS-C172359 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1D2
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TRIM2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TRIM2.

Anti-KIAA0517 / TRIM2 Antibody (clone 4D6) - LS-C172520 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4D6
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TRIM2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TRIM2.

Anti-KIAA0517 / TRIM2 Antibody (aa758-771) IHC-plus™ - LS-B4967 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-TRIM2 / RNF86 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4967 concentration 6.25 ug/ml.

Anti-KIAA0517 / TRIM2 Antibody (clone 1D12) - LS-C172380 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1D12
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TRIM2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TRIM2.

Anti-KIAA0517 / TRIM2 Antibody (clone 4E5) - LS-C172355 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4E5
Western blot of extracts (35 ug) from 9 different cell lines by using anti-TRIM2 monoclonal antibody.

Anti-KIAA0517 / TRIM2 Antibody (clone 3B5) - LS-C337142 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3B5
Immunofluorescent staining of HeLa cells using anti-TRIM2 mouse monoclonal antibody.

Anti-KIAA0517 / TRIM2 Antibody (clone 2B10) - LS-C172384 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2B10
Western blot of extracts (35 ug) from 9 different cell lines by using anti-TRIM2 monoclonal antibody.

Anti-KIAA0517 / TRIM2 Antibody (aa592-621) - LS-C160178 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
TRIM2 Antibody western blot of U251 cell line lysates (35 ug/lane). The TRIM2 antibody detected the TRIM2 protein (arrow).

Anti-KIAA0517 / TRIM2 Antibody (clone 5G7) - LS-C172358 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 5G7
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TRIM2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TRIM2.

Anti-KIAA0517 / TRIM2 Antibody (aa592-621, AP) - LS-C272168 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KIAA0517 / TRIM2 Antibody (aa592-621, APC) - LS-C272169 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KIAA0517 / TRIM2 Antibody (aa592-621, Biotin) - LS-C272170 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KIAA0517 / TRIM2 Antibody (aa592-621, FITC) - LS-C272171 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KIAA0517 / TRIM2 Antibody (aa592-621, Azide-free, HRP) - LS-C272172 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KIAA0517 / TRIM2 Antibody (aa233-247) - LS-C139773 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
TRIM2 antibody (0.1 ug/ml) staining of Mouse Brain lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-KIAA0517 / TRIM2 Antibody (aa592-621, PE) - LS-C272173 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KIAA0517 / TRIM2 Antibody (aa591-621) - LS-C325933 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

TRIM2 Antibody - NB100-1218 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: TRIM2 Antibody [NB100-1218] - Staining of Rat Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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