Gene Symbol | ALX1 |
---|---|
Entrez Gene | 8092 |
Alt Symbol | CART1, FND3, HEL23 |
Species | Human |
Gene Type | protein-coding |
Description | ALX homeobox 1 |
Other Description | ALX homeobox protein 1|CART-1|cartilage paired-class homeoprotein 1|epididymis luminal protein 23 |
Swissprots | Q15699 Q96FH4 Q546C8 |
Accessions | CAD90155 EAW97398 Q15699 BC010923 AAH10923 EU794597 ACJ13651 U31986 AAB08960 XM_005269165 XP_005269222 XM_011538782 XP_011537084 XM_011538783 XP_011537085 NM_006982 NP_008913 |
Function | Transcriptional activator that acts at a palindromic recognition sequence to enhance the activity of the SV40 and TK promoters. Functions as a repressor with the prolactin promoter in vivo. May play a role in chondrocyte differentiation and may also influence cervix development. {ECO:0000269|PubMed:9753625}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00138, ECO:0000269|PubMed:9753625}. |
Tissue Specificity | Cartilage and cervix tissue. |