Gene Symbol | ALX1 |
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Entrez Gene | 8092 |
Alt Symbol | CART1, FND3, HEL23 |
Species | Human |
Gene Type | protein-coding |
Description | ALX homeobox 1 |
Other Description | ALX homeobox protein 1|CART-1|cartilage paired-class homeoprotein 1|epididymis luminal protein 23 |
Swissprots | Q15699 Q96FH4 Q546C8 |
Accessions | CAD90155 EAW97398 Q15699 BC010923 AAH10923 EU794597 ACJ13651 U31986 AAB08960 XM_005269165 XP_005269222 XM_011538782 XP_011537084 XM_011538783 XP_011537085 NM_006982 NP_008913 |
Function | Transcriptional activator that acts at a palindromic recognition sequence to enhance the activity of the SV40 and TK promoters. Functions as a repressor with the prolactin promoter in vivo. May play a role in chondrocyte differentiation and may also influence cervix development. {ECO:0000269|PubMed:9753625}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108, ECO:0000255|PROSITE-ProRule:PRU00138, ECO:0000269|PubMed:9753625}. |
Tissue Specificity | Cartilage and cervix tissue. |
ALX1 CRISPR/Cas9 KO Plasmid (h) - sc-409564 from Santa Cruz Biotechnology
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ALX1 HDR Plasmid (h) - sc-409564-HDR from Santa Cruz Biotechnology
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ALX1 Double Nickase Plasmid (h) - sc-409564-NIC from Santa Cruz Biotechnology
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ALX1 Double Nickase Plasmid (h2) - sc-409564-NIC-2 from Santa Cruz Biotechnology
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ALX1 CRISPR Activation Plasmid (h) - sc-409564-ACT from Santa Cruz Biotechnology
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ALX1 CRISPR Activation Plasmid (h2) - sc-409564-ACT-2 from Santa Cruz Biotechnology
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ALX1 Lentiviral Activation Particles (h) - sc-409564-LAC from Santa Cruz Biotechnology
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ALX1 Lentiviral Activation Particles (h2) - sc-409564-LAC-2 from Santa Cruz Biotechnology
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ALX1 siRNA (h) - sc-96179 from Santa Cruz Biotechnology
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ALX1 shRNA Plasmid (h) - sc-96179-SH from Santa Cruz Biotechnology
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ALX1 shRNA (h) Lentiviral Particles - sc-96179-V from Santa Cruz Biotechnology
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CART1 RNAi - H00008092-R01 from Novus Biologicals
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MISSION® esiRNA - EHU001841 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3095 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3095 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03562 from Sigma-Aldrich
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ALX1 siRNA (Human) - CRH5367 from Cohesion Biosciences
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ALX1 - MBS8216722 from MyBioSource
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shRNA set against Human ALX1 (NM_006982.2) - SHH235570 from Creative biogene
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Human ALX1 siRNA - orb265869 from Biorbyt
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ALX1 shRNA Plasmid (Human) - CHH5367 from Cohesion Biosciences
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ALX1 miRNA 3'UTR clone - MiUTR4H-TG10541 from Creative biogene
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