| Gene Symbol |
PSMA5
|
| Entrez Gene |
5686
|
| Alt Symbol |
PSC5, ZETA
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
proteasome (prosome, macropain) subunit, alpha type, 5
|
| Other Description |
macropain subunit zeta|macropain zeta chain|multicatalytic endopeptidase complex zeta chain|proteasome alpha 5 subunit|proteasome component 5|proteasome subunit alpha type-5|proteasome subunit zeta|proteasome zeta chain
|
| Swissprots |
P28066 B2R8F6 Q6IBF7 B4E2V4 Q3T1C1
|
| Accessions |
EAW56381 EAW56382 EAW56383 P28066 AK124307 AK225990 AK304448 BAG65266 AK313351 BAG36153 BC018605 BC102018 AAI02019 BC102019 AAI02020 BC102020 AAI02021 BC103751 AAI03752 BG743267 BI825400 BM793388 BT019717 AAV38522 CR456847 CAG33128 DC320780 DC324021 DC324498 H08369 X61970 CAA43962 NM_001199772 NP_001186701 NM_001199773 NP_001186702 NM_001199774 NP_001186703 NM_002790 NP_002781
|
| Function |
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
|
| Subcellular Location |
Cytoplasm. Nucleus.
|
| Tissue Specificity |
Expressed in fetal brain (at protein level). {ECO:0000269|PubMed:11771738}.
|
| Top Pathways |
Proteasome
|