Gene Symbol | PSMA5 |
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Entrez Gene | 5686 |
Alt Symbol | PSC5, ZETA |
Species | Human |
Gene Type | protein-coding |
Description | proteasome (prosome, macropain) subunit, alpha type, 5 |
Other Description | macropain subunit zeta|macropain zeta chain|multicatalytic endopeptidase complex zeta chain|proteasome alpha 5 subunit|proteasome component 5|proteasome subunit alpha type-5|proteasome subunit zeta|proteasome zeta chain |
Swissprots | P28066 B2R8F6 Q6IBF7 B4E2V4 Q3T1C1 |
Accessions | EAW56381 EAW56382 EAW56383 P28066 AK124307 AK225990 AK304448 BAG65266 AK313351 BAG36153 BC018605 BC102018 AAI02019 BC102019 AAI02020 BC102020 AAI02021 BC103751 AAI03752 BG743267 BI825400 BM793388 BT019717 AAV38522 CR456847 CAG33128 DC320780 DC324021 DC324498 H08369 X61970 CAA43962 NM_001199772 NP_001186701 NM_001199773 NP_001186702 NM_001199774 NP_001186703 NM_002790 NP_002781 |
Function | The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. |
Subcellular Location | Cytoplasm. Nucleus. |
Tissue Specificity | Expressed in fetal brain (at protein level). {ECO:0000269|PubMed:11771738}. |
Top Pathways | Proteasome |
20S Proteasome α5 CRISPR/Cas9 KO Plasmid (h) - sc-402312 from Santa Cruz Biotechnology
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20S Proteasome α5 HDR Plasmid (h) - sc-402312-HDR from Santa Cruz Biotechnology
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20S Proteasome α5 Double Nickase Plasmid (h) - sc-402312-NIC from Santa Cruz Biotechnology
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20S Proteasome α5 Double Nickase Plasmid (h2) - sc-402312-NIC-2 from Santa Cruz Biotechnology
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20S Proteasome α5 CRISPR Activation Plasmid (h) - sc-402312-ACT from Santa Cruz Biotechnology
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20S Proteasome α5 CRISPR Activation Plasmid (h2) - sc-402312-ACT-2 from Santa Cruz Biotechnology
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20S Proteasome α5 Lentiviral Activation Particles (h) - sc-402312-LAC from Santa Cruz Biotechnology
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20S Proteasome α5 Lentiviral Activation Particles (h2) - sc-402312-LAC-2 from Santa Cruz Biotechnology
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20S Proteasome α5 siRNA (h) - sc-62882 from Santa Cruz Biotechnology
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20S Proteasome α5 shRNA Plasmid (h) - sc-62882-SH from Santa Cruz Biotechnology
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20S Proteasome α5 shRNA (h) Lentiviral Particles - sc-62882-V from Santa Cruz Biotechnology
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Proteasome 20S alpha 5 RNAi - H00005686-R01 from Novus Biologicals
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MISSION® esiRNA - EHU043991 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17592 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17592 from Sigma-Aldrich
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PSMA5 siRNA (Human) - CRH3833 from Cohesion Biosciences
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shRNA set against Human PSMA5 (NM_002790.3) - SHH385088 from Creative biogene
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Human PSMA5 siRNA - orb264335 from Biorbyt
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PSMA5 shRNA Plasmid (Human) - CHH3833 from Cohesion Biosciences
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PSMA5 miRNA 3'UTR clone - MiUTR3H-01866 from Creative biogene
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