| Gene Symbol |
AVIL
|
| Entrez Gene |
10677
|
| Alt Symbol |
ADVIL, DOC6, p92
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
advillin
|
| Other Description |
-
|
| Swissprots |
O75366 Q2NKM9 B2RAU7
|
| Accessions |
EAW97079 EAW97080 O75366 AF041449 AAC25051 AK022448 AK314362 BAG36994 BC111730 AAI11731 BX647344 XM_011537766 XP_011536068 XM_011537767 XP_011536069 XM_011537768 XP_011536070 XM_011537769 XP_011536071 XM_011537770 XP_011536072 XM_011537771 XP_011536073 XM_011537772 XP_011536074 NM_006576 NP_006567
|
| Function |
Ca(2+)-regulated actin-binding protein. May have a unique function in the morphogenesis of neuronal cells which form ganglia. Required for SREC1-mediated regulation of neurite-like outgrowth. Plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates. Involved in the formation of long fine actin-containing filopodia-like structures in fibroblast. Plays a role in ciliogenesis. {ECO:0000269|PubMed:20393563}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton. Cell projection {ECO:0000250}. Cell projection, axon {ECO:0000250}.
|
| Tissue Specificity |
Most highly expressed in the small intestine and colonic lining. Weaker expression also detected in the thymus, prostate, testes and uterus. {ECO:0000269|PubMed:12034507}.
|