Gene Symbol | AVIL |
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Entrez Gene | 10677 |
Alt Symbol | ADVIL, DOC6, p92 |
Species | Human |
Gene Type | protein-coding |
Description | advillin |
Other Description | - |
Swissprots | O75366 Q2NKM9 B2RAU7 |
Accessions | EAW97079 EAW97080 O75366 AF041449 AAC25051 AK022448 AK314362 BAG36994 BC111730 AAI11731 BX647344 XM_011537766 XP_011536068 XM_011537767 XP_011536069 XM_011537768 XP_011536070 XM_011537769 XP_011536071 XM_011537770 XP_011536072 XM_011537771 XP_011536073 XM_011537772 XP_011536074 NM_006576 NP_006567 |
Function | Ca(2+)-regulated actin-binding protein. May have a unique function in the morphogenesis of neuronal cells which form ganglia. Required for SREC1-mediated regulation of neurite-like outgrowth. Plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates. Involved in the formation of long fine actin-containing filopodia-like structures in fibroblast. Plays a role in ciliogenesis. {ECO:0000269|PubMed:20393563}. |
Subcellular Location | Cytoplasm, cytoskeleton. Cell projection {ECO:0000250}. Cell projection, axon {ECO:0000250}. |
Tissue Specificity | Most highly expressed in the small intestine and colonic lining. Weaker expression also detected in the thymus, prostate, testes and uterus. {ECO:0000269|PubMed:12034507}. |
advillin CRISPR/Cas9 KO Plasmid (h) - sc-411502 from Santa Cruz Biotechnology
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advillin HDR Plasmid (h) - sc-411502-HDR from Santa Cruz Biotechnology
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advillin Double Nickase Plasmid (h) - sc-411502-NIC from Santa Cruz Biotechnology
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advillin Double Nickase Plasmid (h2) - sc-411502-NIC-2 from Santa Cruz Biotechnology
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advillin CRISPR Activation Plasmid (h) - sc-411502-ACT from Santa Cruz Biotechnology
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advillin CRISPR Activation Plasmid (h2) - sc-411502-ACT-2 from Santa Cruz Biotechnology
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advillin Lentiviral Activation Particles (h) - sc-411502-LAC from Santa Cruz Biotechnology
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advillin Lentiviral Activation Particles (h2) - sc-411502-LAC-2 from Santa Cruz Biotechnology
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advillin siRNA (h) - sc-72458 from Santa Cruz Biotechnology
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advillin shRNA Plasmid (h) - sc-72458-SH from Santa Cruz Biotechnology
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advillin shRNA (h) Lentiviral Particles - sc-72458-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU016181 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3777 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3777 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00853 from Sigma-Aldrich
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AVIL siRNA (Human) - CRH7282 from Cohesion Biosciences
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AVIL - MBS8221401 from MyBioSource
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shRNA set against Human AVIL (NM_006576.3) - SHH243802 from Creative biogene
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shRNA set against Human AVIL(NM_006576.3) - SHG086905 from Creative biogene
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AVIL shRNA Plasmid (Human) - CHH7282 from Cohesion Biosciences
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AVIL miRNA 3'UTR clone - MiUTR1H-00751 from Creative biogene
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