Gene Symbol | VASH1 |
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Entrez Gene | 22846 |
Alt Symbol | KIAA1036 |
Species | Human |
Gene Type | protein-coding |
Description | vasohibin 1 |
Other Description | vasohibin-1 |
Swissprots | Q9UBF4 Q7L8A9 Q96H02 Q9Y629 |
Accessions | AAD44361 AAF02829 EAW81259 EAW81260 Q7L8A9 AB028959 BAA82988 AF055021 AK094330 AK291377 BAF84066 AL041425 AL832588 CAD89941 BC009031 AAH09031 BC051896 AAH51896 BE674799 BF741850 XM_006720080 XP_006720143 XM_011536556 XP_011534858 XM_011536557 XP_011534859 XM_011536558 XP_011534860 XM_011536559 XP_011534861 XM_011536560 XP_011534862 XM_011536561 XP_011534863 XM_011536562 XP_011534864 NM_014909 NP_055724 |
Function | Angiogenesis inhibitor. Inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts. Does not affect the proliferation of cancer cells in vitro, but inhibits tumor growth and tumor angiogenesis. Acts in an autocrine manner. Inhibits artery neointimal formation and macrophage infiltration. Exhibits heparin-binding activity. {ECO:0000269|PubMed:15467828, ECO:0000269|PubMed:16488400, ECO:0000269|PubMed:16707096}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:15467828, ECO:0000269|PubMed:16707096}. |
Tissue Specificity | Preferentially expressed in endothelial cells. Highly expressed in fetal organs. Expressed in brain and placenta, and at lower level in heart and kidney. Highly detected in microvessels endothelial cells of atherosclerotic lesions. {ECO:0000269|PubMed:15467828, ECO:0000269|PubMed:16707096}. |
Human VASH1 full length protein - ab153190 from Abcam
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Vasohibin 1 / VASH1 Antibody Blocking Peptide - LS-E19895 from LifeSpan Bioscience
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Vasohibin 1 / VASH1 Antibody Blocking Peptide - LS-E19896 from LifeSpan Bioscience
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Vasohibin 1 / VASH1 Antibody Blocking Peptide - LS-E31122 from LifeSpan Bioscience
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Recombinant Human Vasohibin Protein - H00022846-P01 from Novus Biologicals
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Recombinant Human Vasohibin Protein - H00022846-Q01 from Novus Biologicals
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Vasohibin Blocking Peptide - NBP1-76579PEP from Novus Biologicals
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Human VASH1 protein - orb246576 from Biorbyt
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Vasohibin 1 Blocking Peptide - 33R-8923 from Fitzgerald
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Vasohibin 1 Blocking Peptide - 33R-1576 from Fitzgerald
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Vasohibin-1 / VASH1 - H00022846-P01-10 from Acris Antibodies
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Vasohibin-1 / VASH1 - H00022846-P01-25 from Acris Antibodies
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Vasohibin-1 / VASH1 - H00022846-Q01-10 from Acris Antibodies
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Vasohibin-1 / VASH1 - H00022846-Q01-25 from Acris Antibodies
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Vasohibin-1 / VASH1 control peptide - AP26144CP-N from Acris Antibodies
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VASH1 Peptide - 6325P from ProSci
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VASH1 fusion protein - Ag3435 from Proteintech Group
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Recombinant Human VASH1, GST-tagged - VASH1-3649H from Creative Biomart
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Vasohibin (R302) Peptide - BS9217P from Bioworld Technology
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Recombinant Human Vasohibin-1(VASH1) - CSB-YP745337HU CSB-BP745337HU CSB-MP745337HU from Cusabio
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Recombinant human Vasohibin-1 - CSB-EP745337HU from Cusabio
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Vasohibin-1 / VASH1 - TP308728 from Acris Antibodies
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Vasohibin-1 (VASH1) , Recombinant Protein - MBS1466359 from MyBioSource
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Vasohibin Recombinant Protein Antigen - NBP1-82944PEP from Novus Biologicals
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VASH1 Peptide, Human - M34GP17238H from Creative Peptides
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