| Gene Symbol |
PEAK1
|
| Entrez Gene |
79834
|
| Alt Symbol |
SGK269
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
pseudopodium-enriched atypical kinase 1
|
| Other Description |
NKF3 kinase family member|sugen kinase 269|tyrosine-protein kinase SgK269
|
| Swissprots |
Q8NAZ4 Q6ZS78 Q8TEG7 Q8NCM3 Q9H792
|
| Accessions |
Q9H792 AB082533 BAC02711 AF086416 AF088077 AK024793 BAB15006 AK025943 AK074157 BAB84983 AK091802 AK124548 AK127658 BAC87076 AW069191 BC172320 AAI72320 BX953442 DA651665 XM_005254670 XP_005254727 XM_005254671 XP_005254728 XM_005254673 XP_005254730 XM_005254674 XP_005254731 XM_005254675 XP_005254732 XM_011522033 XP_011520335 XM_011522034 XP_011520336 XM_011522035 XP_011520337 XM_011522036 XP_011520338 XM_011522037 XP_011520339 XM_011522038 XP_011520340 XM_011522039 XP_011520341 XM_011522040 XP_011520342 XM_011522041 XP_011520343 XM_011522042 XP_011520344 NM_024776 NP_079052
|
| Function |
Tyrosine kinase that may play a role in cell spreading and migration on fibronectin. May directly or indirectly affect phosphorylation levels of cytoskeleton-associated proteins MAPK1/ERK and PXN. {ECO:0000269|PubMed:20534451}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton {ECO:0000269|PubMed:20534451}. Cell junction, focal adhesion {ECO:0000269|PubMed:20534451}. Note=Colocalizes with F-actin in serum-rich medium. Actin colocalization is reduced during serum starvation.
|