ADGRE2

Gene Symbol ADGRE2
Entrez Gene 30817
Alt Symbol CD312, EMR2
Species Human
Gene Type protein-coding
Description adhesion G protein-coupled receptor E2
Other Description EGF-like module-containing mucin-like hormone receptor-like 2|egf-like module containing, mucin-like, hormone receptor-like 2
Swissprots E9PFQ5 E9PEL6 B4DQ96 E7ESD7 Q9Y4B1 E9PBR1 Q8NG96 Q9UHX3 E9PG91
Accessions AAC05172 AAC27673 BAC06146 EAW84445 EAW84446 EAW84447 EAW84448 Q9UHX3 AF114491 AAF21974 AK024426 BAB15716 AK024454 BAB15744 AK222891 BAD96611 AK291776 BAF84465 AK298690 BAG60850 AK298700 BAG60858 AK301458 BAG62980 BC034949 AAH34949 BC053933 AAH53933 BC082991 BC127004 AAI27005 BC127005 AAI27006 BG720310 BG721006 CN480316 CR936819 XM_011527948 XP_011526250 XM_011527949 XP_011526251 XM_011527950 XP_011526252 XM_011527951 XP_011526253 XM_011527952 XP_011526254 XM_011527953 XP_011526255 XM_011527954 XP_011526256 XM_011527955 XP_011526257 XR_936171 XR_936172 XR_936173 XR_936174 NM_001271052 NP_001257981 NM_013447 NP_038475 NM_152916 NM_152917 NM_152918 NM_152919 NM_152920 NM_152921
Function Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF. {ECO:0000269|PubMed:12829604, ECO:0000269|PubMed:17928360, ECO:0000269|PubMed:22310662}.
Subcellular Location Cell membrane; Multi-pass membrane protein. Cell projection, ruffle membrane; Multi-pass membrane protein. Note=Localized at the leading edge of migrating cells.
Tissue Specificity Expression is restricted to myeloid cells. Highest expression was found in peripheral blood leukocytes, followed by spleen and lymph nodes, with intermediate to low levels in thymus, bone marrow, fetal liver, placenta, and lung, and no expression in heart, brain, skeletal muscle, kidney, or pancreas. Expression is also detected in monocyte/macrophage and Jurkat cell lines but not in other cell lines tested. {ECO:0000269|PubMed:10903844, ECO:0000269|PubMed:11994511}.

EMR2 (H-210) - sc-367783 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

EMR2 (L-17) - sc-34334 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
EMR2 (L-17): sc-34334. Western blot analysis of EMR2 expression in Jurkat whole cell lysate.

EMR2 (A-20) - sc-34336 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

cleaved EMR2 (h517) - sc-34323 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

cleaved EMR2 (h518) - sc-34324 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-EMR2 antibody - ab200686 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-EMR2 antibody (ab200686)Lane 1 : HEK293T whole cell lysateLane 2 : Raw 264.7 whole cell lysateLane 3 : PC12 whole cell lysate

Anti-EMR2 antibody - ab75190 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-EMR2 antibody (ab75190) at 1/500 dilutionLane 1 : HeLa cell extractLane 2 : HeLa cell extract with immunising peptide at 10 µgLysates/proteins at 10 µg per lane.

Anti-EMR2 antibody - ab136098 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-EMR2 antibody (ab136098) at 1/500 dilution + HUVEC cell lysate at 30 µg

Anti-EMR2 antibody - ab122999 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-EMR2 antibody (ab122999) at 1 µg/ml + PANC1 cell lysate at 10 µg

Anti-EMR2 antibody - N-terminal - ab150481 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin embedded Human lung, pneumonia, neutrophils tissue labelling EMR2 with ab150481 antibody at a concentration of 14 µg/ml.

Anti-ADGRE2 / EMR2 Antibody (N-Terminus) IHC-plus™ - LS-A6319 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-EMR2 antibody LS-A6319 IHC of human lung, pneumonia, neutrophils. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-ADGRE2 / EMR2 Antibody - LS-C123201 from LifeSpan Bioscience

Prices $725.00
Sizes 500 µg
Host Mouse
Clonality Monoclonal

Anti-ADGRE2 / EMR2 Antibody (Biotin) - LS-C125313 from LifeSpan Bioscience

Prices $650.00
Sizes 50 µg
Host Sheep
Clonality Polyclonal

Anti-ADGRE2 / EMR2 Antibody (APC) - LS-C125335 from LifeSpan Bioscience

Prices $590.00
Sizes 100 tst
Host Mouse
Clonality Monoclonal

Anti-ADGRE2 / EMR2 Antibody (Biotin) - LS-C128041 from LifeSpan Bioscience

Prices $560.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-ADGRE2 / EMR2 Antibody (FITC) - LS-C128042 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-ADGRE2 / EMR2 Antibody (PE) - LS-C128043 from LifeSpan Bioscience

Prices $545.00
Sizes 100 tst
Host Mouse
Clonality Monoclonal

Anti-ADGRE2 / EMR2 Antibody (N-Terminus) IHC-plus™ - LS-A6306 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-EMR2 antibody LS-A6306 IHC of human lung, neutrophils. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-ADGRE2 / EMR2 Antibody - LS-C153200 from LifeSpan Bioscience

Prices $410.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ADGRE2 / EMR2 Antibody (clone 2A1) - LS-C188288 from LifeSpan Bioscience

Prices $575.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone 2A1
Flow cytometry of human peripheral blood granulocytes with Mouse anti-Human CD312

Anti-ADGRE2 / EMR2 Antibody (aa121-170) - LS-C120649 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from HeLa cells, using EMR2 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-ADGRE2 / EMR2 Antibody (aa790) - LS-C190186 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-ADGRE2 / EMR2 Antibody (clone 2A1, Biotin) - LS-C188289 from LifeSpan Bioscience

Prices $535.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2A1
Flow cytometry of human peripheral blood monocytes with Mouse anti-Human CD312: Biotin

Anti-ADGRE2 / EMR2 Antibody (aa92-141) - LS-C145934 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
EMR2 antibody LS-C145934 Western blot of PANC1 Cell lysate. Antibody concentration 1 ug/ml.

Anti-ADGRE2 / EMR2 Antibody IHC-plus™ - LS-B8033 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Anti-EMR2 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8033 dilution 10 ug/ml.
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