Chst3

Gene Symbol Chst3
Entrez Gene 53374
Alt Symbol C6ST, C6ST-1, GST-0
Species Mouse
Gene Type protein-coding
Description carbohydrate (chondroitin 6/keratan) sulfotransferase 3
Other Description carbohydrate sulfotransferase 3|chondroitin 6-O-sulfotransferase 1|chondroitin 6-sulfotransferase|galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0
Swissprots Q794I5 O88199
Accessions BAB72166 EDL32179 EDL32180 O88199 AB008937 BAA29054 AB008938 BAA29055 AK134391 BC055055 AAH55055 BP757294 CJ142827 XM_011243510 XP_011241812 XM_011243511 XP_011241813 XM_011243512 XP_011241814 XM_011243513 XP_011241815 NM_016803 NP_058083
Function Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Can also sulfate Gal residues of keratan sulfate, another glycosaminoglycan, and the Gal residues in sialyl N- acetyllactosamine (sialyl LacNAc) oligosaccharides. May play a role in the maintenance of naive T-lymphocytes in the spleen. {ECO:0000269|PubMed:11696535, ECO:0000269|PubMed:9597547}.
Subcellular Location Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity Widely expressed. Highly expressed in spleen, lung, eye and stomach. Constitutively expressed at low level during the mid- to late-gestation period. Expressed in the brain in a temporally controlled manner: peaks at 2 weeks after birth in the cerebellum, but at 3 weeks in the cerebrum. Localizes to stromal cells in the bone marrow, and stromal cells in the marginal zone and red pulp of the spleen, but the sense probe did not. {ECO:0000269|PubMed:9597547}.
Top Pathways Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate

Recombinant Mouse CHST3, CF - 5356-ST-020 from R&D Systems

Category Protein
Source Chinese Hamster Ovary cell line, CHO-derived, Glu39-Thr472, with an N-terminal 6-His tag

Mouse C6ST 1 protein - orb84130 from Biorbyt

Category Protein
Prices $400.00, $612.00
Sizes 20 μg, 50 μg
Source Human
Species Mouse
SDS-PAGE analysis of mouse CHST3 His tag protein

Recombinant Mouse Chst3, His-tagged - Chst3-705M from Creative Biomart

Category Protein
Source CHO Cells
Species Mouse

Recombinant Mouse Chst3, His tagged - Chst3-4046M from Creative Biomart

Category Protein
Source Human Cells
Species Mouse

CHST3 - PN201312 from Elabscience

Category Protein
Prices $225.00, $475.00
Sizes 10 μg, 50 μg
Source Human Cells
Species Mouse

Mouse CHST3 / C6ST-1 Protein (His Tag) - 50577-M07H-20 from Sino Biological

Category Protein
Source Human Cells
Species Mouse

Recombinant Mouse Carbohydrate sulfotransferase 3(Chst3) - CSB-YP005409MO CSB-EP005409MO CSB-BP005409MO CSB-MP005409MO from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Mouse

Recombinant Mouse CHST3 Protein, CF - 5356-ST from R&D Systems

Category Protein
Prices $329.00
Sizes 20 µg
Source Chinese Hamster Ovary cell line, CHO-derived Glu39-Thr472, with an N-terminal 6-His tag
Species Mouse

Carbohydrate sulfotransferase 3 (Chst3), Recombinant Protein - MBS1226031 from MyBioSource

Category Protein
Prices $2,000.00, $2,455.00
Sizes 1 mg (E-Coli), 1 mg (Yeast)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Mouse

Recombinant Mouse CHST3 / C6ST-1 Protein (His tag) - PKSM040601 from Elabscience

Category Protein
Source Human Cell
Species Mouse

Mouse CHST3 / C6ST-1 Protein (His Tag) - 50577-M07H from ABclonal

Category Protein
Prices $178.00, $298.00
Sizes 20 µg, 50 µg
Source Human Cells
Species Mouse

Carbohydrate sulfotransferase 3, Recombinant Protein - MBS7042559 from MyBioSource

Category Protein
Prices $1,275.00, $2,260.00, $3,465.00
Sizes 10 µg, 50 µg, 100 µg
Source Cell Free Expression
Species Mouse

CHST3 / C6ST-1, Recombinant Protein - MBS2546903 from MyBioSource

Category Protein
Prices $475.00, $775.00
Sizes 20 µg, 50 µg
Source Human Cells
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