POGLUT1

Gene Symbol	POGLUT1
Entrez Gene	56983
Alt Symbol	C3orf9, CLP46, KDELCL1, KTELC1, MDS010, MDSRP, Rumi, hCLP46
Species	Human
Gene Type	protein-coding
Description	protein O-glucosyltransferase 1
Other Description	9630046K23Rik|CAP10-like 46 kDa protein|KDELC family like 1|KTEL (Lys-Tyr-Glu-Leu) containing 1|KTEL motif-containing protein 1|O-glucosyltransferase Rumi homolog|hRumi|myelodysplastic syndromes relative protein|protein O-xylosyltransferase|x 010 protein
Swissprots	Q8NBL1 Q8N2T1 Q53GJ4 B2RD13
Accessions	CAI72128 EAW79570 Q8NBL1 AF168711 AAF87313 AK027012 AK075444 BAC11625 AK126736 AK222937 BAD96657 AK295984 BAG58759 AK301002 BAG62621 AK315367 BAG37760 AY298903 AAP56253 AY358581 AAQ88944 BC030614 AAH30614 BC048810 AAH48810 BP347179 CD517010 HQ447221 ADQ31708 XM_006713704 XP_006713767 XM_006713705 XP_006713768 XM_011512997 XP_011511299 NM_152305 NP_689518 NR_024265
Function	Dual specificity glycosyltransferase. Catalyzes the transfer of glucose and xylose from UDP-glucose and UDP-xylose, respectively, to EGF repeats, such as those found in F7, F9 and NOTCH2, on the consensus sequence C-X-S-X-P-C. Positively regulates Notch signaling without affecting Notch ligand binding. {ECO:0000269|PubMed:21081508, ECO:0000269|PubMed:21490058, ECO:0000269|PubMed:21949356}.
Subcellular Location	Endoplasmic reticulum lumen {ECO:0000269|PubMed:16524674, ECO:0000269|PubMed:24387993}.
Tissue Specificity	Expressed in most adult tissues at different intensities. Abundantly expressed in liver. Expressed also in brain, heart, skeletal muscle, spleen, kidney, placenta, lung and peripheral blood leukocyte. Not detectable in colon, thymus and small intestine. Expressed in the epidermis, especially in the upper parts, stratum spinosum and stratum granulosum (at protein level). {ECO:0000269|PubMed:16524674, ECO:0000269|PubMed:24387993}.
Top Pathways	Other types of O-glycan biosynthesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

POGLUT1 Antibody Blocking Peptide - LS-E10258 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KTEL1-Antibody-C-term-Blocking-Peptide - BP9678b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human POGLUT1, CF - 6437-GT-020 from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived, Met1-Leu388, with a C-terminal 6-His tag

KTELC1 fusion protein - ag19934 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

KTELC1 fusion protein - Ag19942 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human Protein O-glucosyltransferase 1(POGLUT1) - CSB-YP818754HU CSB-BP818754HU CSB-MP818754HU from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Recombinant Human Protein O-glucosyltransferase 1(POGLUT1) - CSB-EP818754HU from Cusabio Category Protein Source Yeast Species Human

Recombinant Human POGLUT1 Protein, CF - 6437-GT from R&D Systems Category Protein Prices $359.00 Sizes 20 µg Source Chinese Hamster Ovary cell line, CHO-derived Met1-Leu388, with a C-terminal 6-His tag Accession # Q8NBL1 Species Human

POGLUT1 / KTELC1 (transcript variant 1) - TP305992 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Protein O-Glucosyltransferase 1/POGLUT1/KTELC1 Protein - NBP1-90311PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

POGLUT1 Peptide, Human - M34GP12060H from Creative Peptides Category Peptide Source Synthetic. Species Human

POGLUT1, 24-392aa, Human, His tag, Baculovirus - ATGP3356 from ATGen Category Protein Prices $80.00, $240.00, $960.00 Sizes 4 µg, 20 µg, 100 µg Species Human

Recombinant Human Protein O-Glucosyltransferase 1/POGLUT1/KTELC1 Protein - NBP2-50569 from Novus Biologicals Category Protein Prices $249.00, $1,000.00 Sizes 20 µg, 100 µg Source Baculovirus Species Human

Protein O-Glucosyltransferase 1, Human Recombinant - 228-20900-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

POGLUT1 - PAT-83336-1 from Nordic BioSite Category Protein

POGLUT1 - PAT-83336-2 from Nordic BioSite Category Protein

O-Glucosyltransferase 1, Recombinant Protein - MBS146804 from MyBioSource Category Protein Prices $140.00, $205.00, $1,220.00 Sizes 1 µg, 5 µg, 50 µg Source Sf9, Baculovirus cells

O-glucosyltransferase rumi homolog (AAEL011121), Recombinant Protein - MBS1436094 from MyBioSource Category Protein Prices $1,150.00, $1,150.00, $1,380.00, $1,380.00, $1,840.00, $1,840.00, $2,300.00, $2,300.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

O-glucosyltransferase rumi homolog (AGAP004267), Recombinant Protein - MBS1119406 from MyBioSource Category Protein Prices $1,150.00, $1,150.00, $1,380.00, $1,380.00, $1,835.00, $1,835.00, $2,300.00, $2,300.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

O-glucosyltransferase rumi homolog (CPIJ013394), Recombinant Protein - MBS1001211 from MyBioSource Category Protein Prices $1,155.00, $1,155.00, $1,380.00, $1,380.00, $1,840.00, $1,840.00, $2,305.00, $2,305.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

POGLUT1, Recombinant Protein - MBS206362 from MyBioSource Category Protein Prices $310.00, $925.00 Sizes 20 µg, 100 µg Source Baculovirus Species Human

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