Gene Symbol | IGFBPL1 |
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Entrez Gene | 347252 |
Alt Symbol | IGFBP-RP4, IGFBPRP4, bA113O24.1 |
Species | Human |
Gene Type | protein-coding |
Description | insulin-like growth factor binding protein-like 1 |
Other Description | IGFBP-related protein 10|insulin-like growth factor binding protein related protein 4|insulin-like growth factor-binding protein-like 1|insulin-like growth factor-binding-related protein 4 |
Swissprots | Q8WX77 |
Accessions | EAW58251 Q8WX77 AK055716 AK131521 BC146371 AAI46372 NM_001007563 NP_001007564 |
Function | IGF-binding proteins prolong the half-life of IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs in cell culture. They alter the interaction of IGFs with their cell surface receptors (By similarity). May be a putative tumor suppressor protein. {ECO:0000250, ECO:0000269|PubMed:15845387}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:15845387}. |
Tissue Specificity | Expressed at the highest level in both brain and testis, with lower levels in the prostate, bladder and lung. {ECO:0000269|PubMed:15845387}. |
IGFBPL1 CRISPR/Cas9 KO Plasmid (h) - sc-415626 from Santa Cruz Biotechnology
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IGFBPL1 HDR Plasmid (h) - sc-415626-HDR from Santa Cruz Biotechnology
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IGFBPL1 Double Nickase Plasmid (h) - sc-415626-NIC from Santa Cruz Biotechnology
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IGFBPL1 Double Nickase Plasmid (h2) - sc-415626-NIC-2 from Santa Cruz Biotechnology
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IGFBPL1 CRISPR Activation Plasmid (h) - sc-415626-ACT from Santa Cruz Biotechnology
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IGFBPL1 CRISPR Activation Plasmid (h2) - sc-415626-ACT-2 from Santa Cruz Biotechnology
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IGFBPL1 Lentiviral Activation Particles (h) - sc-415626-LAC from Santa Cruz Biotechnology
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IGFBPL1 Lentiviral Activation Particles (h2) - sc-415626-LAC-2 from Santa Cruz Biotechnology
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IGFBPL1 siRNA (h) - sc-92508 from Santa Cruz Biotechnology
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IGFBPL1 shRNA Plasmid (h) - sc-92508-SH from Santa Cruz Biotechnology
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IGFBPL1 shRNA (h) Lentiviral Particles - sc-92508-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU138741 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10527 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10527 from Sigma-Aldrich
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IGFBPL1 siRNA (Human) - CRJ7496 from Cohesion Biosciences
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IGFBPL1 - MBS8207748 from MyBioSource
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shRNA set against Human Igfbpl1 (NM_001007563.1) - SHH317613 from Creative biogene
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shRNA set against Human IGFBPL1(NM_001007563.1) - SHL168564 from Creative biogene
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Human IGFBPL1 siRNA - orb277997 from Biorbyt
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IGFBPL1 shRNA Plasmid (Human) - CHJ7496 from Cohesion Biosciences
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IGFBPL1 miRNA 3'UTR clone - MiUTR1H-04844 from Creative biogene
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