| Gene Symbol |
CST6
|
| Entrez Gene |
1474
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cystatin E/M
|
| Other Description |
cystatin 6|cystatin M|cystatin M/E|cystatin-6|cystatin-E|cystatin-M|cysteine proteinase inhibitor
|
| Swissprots |
Q15828 Q540N7
|
| Accessions |
AAN52757 CAM83949 EAW74487 Q15828 AA778147 AI127639 AK092391 BC031334 AAH31334 CR456872 CAG33153 U62800 AAB06566 U81233 AAB61305 NM_001323 NP_001314
|
| Function |
Shows moderate inhibition of cathepsin B but is not active against cathepsin C.
|
| Subcellular Location |
Secreted.
|
| Tissue Specificity |
Restricted to the stratum granulosum of normal skin, the stratum granulosum/spinosum of psoriatic skin, and the secretory coils of eccrine sweat glands. Low expression levels are found in the nasal cavity. {ECO:0000269|PubMed:11348457}.
|