Gene Symbol | CST6 |
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Entrez Gene | 1474 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | cystatin E/M |
Other Description | cystatin 6|cystatin M|cystatin M/E|cystatin-6|cystatin-E|cystatin-M|cysteine proteinase inhibitor |
Swissprots | Q15828 Q540N7 |
Accessions | AAN52757 CAM83949 EAW74487 Q15828 AA778147 AI127639 AK092391 BC031334 AAH31334 CR456872 CAG33153 U62800 AAB06566 U81233 AAB61305 NM_001323 NP_001314 |
Function | Shows moderate inhibition of cathepsin B but is not active against cathepsin C. |
Subcellular Location | Secreted. |
Tissue Specificity | Restricted to the stratum granulosum of normal skin, the stratum granulosum/spinosum of psoriatic skin, and the secretory coils of eccrine sweat glands. Low expression levels are found in the nasal cavity. {ECO:0000269|PubMed:11348457}. |
cystatin E/M CRISPR/Cas9 KO Plasmid (h) - sc-408122 from Santa Cruz Biotechnology
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cystatin E/M HDR Plasmid (h) - sc-408122-HDR from Santa Cruz Biotechnology
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cystatin E/M Double Nickase Plasmid (h) - sc-408122-NIC from Santa Cruz Biotechnology
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cystatin E/M Double Nickase Plasmid (h2) - sc-408122-NIC-2 from Santa Cruz Biotechnology
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cystatin E/M CRISPR Activation Plasmid (h) - sc-408122-ACT from Santa Cruz Biotechnology
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cystatin E/M CRISPR Activation Plasmid (h2) - sc-408122-ACT-2 from Santa Cruz Biotechnology
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cystatin E/M Lentiviral Activation Particles (h) - sc-408122-LAC from Santa Cruz Biotechnology
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cystatin E/M Lentiviral Activation Particles (h2) - sc-408122-LAC-2 from Santa Cruz Biotechnology
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cystatin E/M siRNA (h) - sc-60490 from Santa Cruz Biotechnology
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cystatin E/M shRNA Plasmid (h) - sc-60490-SH from Santa Cruz Biotechnology
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cystatin E/M shRNA (h) Lentiviral Particles - sc-60490-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU000511 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6675 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6675 from Sigma-Aldrich
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CST6 siRNA (Human) - CRH1042 from Cohesion Biosciences
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CST6 - MBS8208115 from MyBioSource
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shRNA set against Human CST6 (NM_001323.3) - SHH270765 from Creative biogene
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CST6 shRNA Plasmid (Human) - CHH1042 from Cohesion Biosciences
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CST6 miRNA 3'UTR clone - MiUTR4H-TG11001 from Creative biogene
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