| Gene Symbol | RDM1 |
|---|---|
| Entrez Gene | 201299 |
| Alt Symbol | RAD52B |
| Species | Human |
| Gene Type | protein-coding |
| Description | RAD52 motif containing 1 |
| Other Description | RAD52 homolog B|RAD52 motif 1|RAD52 motif-containing protein 1 |
| Swissprots | A8MV46 A8RCT0 A8MY68 A8RCW0 A8RCT8 A8MZ92 A8RCS5 A8RCT5 A8RCU8 A0JP55 A8RCW5 Q8NG50 A8RCU3 |
| Accessions | EAW80116 EAW80117 EAW80118 Q8NG50 AA761980 AB080728 BAC02562 AK302782 BAG63986 AW138754 BC032114 BC038301 BC127190 AAI27191 BM559857 BU599050 BX376188 EF488473 ABS86950 EF488474 ABS86951 EF488475 ABS86952 EF488476 ABS86953 EF488477 ABS86954 EF488478 ABS86955 EF488479 ABS86956 EF488480 ABS86957 EF488481 ABS86958 EF488482 ABS86959 EU176448 ABW03899 XM_011524509 XP_011522811 XM_011524510 XP_011522812 XM_011546795 XP_011545097 XM_011546796 XP_011545098 NM_001034836 NP_001030008 NM_001163120 NP_001156592 NM_001163121 NP_001156593 NM_001163122 NP_001156594 NM_001163124 NP_001156596 NM_001163125 NP_001156597 NM_001163130 NP_001156602 NM_145654 NP_663629 NR_027996 NR_027997 NR_027998 NR_027999 NR_028000 |
| Function | May confer resistance to the antitumor agent cisplatin. Binds to DNA and RNA. {ECO:0000269|PubMed:15611051}. |
| Subcellular Location | Nucleus {ECO:0000269|PubMed:17905820}. Cytoplasm {ECO:0000269|PubMed:17905820}. Nucleus, nucleolus {ECO:0000269|PubMed:17905820}. Note=Isoform 3 and isoform 10 are predominantly nuclear and nucleolar. After treatment with proteasomal inhibitors and mild heat-shock stress, isoform 1, isoform 3, isoform 5, isoform 7, isoform 8 and isoform 10 are relocalized to the nucleolus as dot-like or irregular subnuclear structures. Isoform 1 colocalized with nuclear promyelocytic leukemia (PML) and Cajal bodies (CB); this association with nuclear bodies is enhanced in response to proteotoxic stress. Isoform 3, but not isoform 1 and isoform 5, is relocalized in nucleolar caps during transcriptional arrest. |
| Tissue Specificity | Expressed in testis. {ECO:0000269|PubMed:15611051}. |
RAD52 motif-containing protein 1 (RDM1), Human, ELISA Kit - E01R0400 from ARP American Research Products
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RAD52 motif containing protein 1 (RDM1), ELISA Kit - MBS7205678 from MyBioSource
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RAD52 motif-containing protein 1 (RDM1), ELISA Kit - MBS7248134 from MyBioSource
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RAD52 motif-containing protein 1 (RDM1), ELISA Kit - MBS7200012 from MyBioSource
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RAD52 motif-containing protein 1 (RDM1), ELISA Kit - MBS7220771 from MyBioSource
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RAD52 motif-containing protein 1 (RDM1), ELISA Kit - MBS7241775 from MyBioSource
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RAD52 motif-containing protein 1 (RDM1), ELISA Kit - MBS7223354 from MyBioSource
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RAD52 motif-containing protein 1 (RDM1), ELISA Kit - MBS7217216 from MyBioSource
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RAD52 motif-containing protein 1 (RDM1), ELISA Kit - MBS7246415 from MyBioSource
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RAD52 motif-containing protein 1 (RDM1), ELISA Kit - MBS7252319 from MyBioSource
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RAD52 motif-containing protein 1 (RDM1), ELISA Kit - MBS7243380 from MyBioSource
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RAD52 motif-containing protein 1 (RDM1), ELISA Kit - MBS7247315 from MyBioSource
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Human RDM1 ELISA Kit - E032750 from Biobool
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