Gene Symbol | RDM1 |
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Entrez Gene | 201299 |
Alt Symbol | RAD52B |
Species | Human |
Gene Type | protein-coding |
Description | RAD52 motif containing 1 |
Other Description | RAD52 homolog B|RAD52 motif 1|RAD52 motif-containing protein 1 |
Swissprots | A8MV46 A8RCT0 A8MY68 A8RCW0 A8RCT8 A8MZ92 A8RCS5 A8RCT5 A8RCU8 A0JP55 A8RCW5 Q8NG50 A8RCU3 |
Accessions | EAW80116 EAW80117 EAW80118 Q8NG50 AA761980 AB080728 BAC02562 AK302782 BAG63986 AW138754 BC032114 BC038301 BC127190 AAI27191 BM559857 BU599050 BX376188 EF488473 ABS86950 EF488474 ABS86951 EF488475 ABS86952 EF488476 ABS86953 EF488477 ABS86954 EF488478 ABS86955 EF488479 ABS86956 EF488480 ABS86957 EF488481 ABS86958 EF488482 ABS86959 EU176448 ABW03899 XM_011524509 XP_011522811 XM_011524510 XP_011522812 XM_011546795 XP_011545097 XM_011546796 XP_011545098 NM_001034836 NP_001030008 NM_001163120 NP_001156592 NM_001163121 NP_001156593 NM_001163122 NP_001156594 NM_001163124 NP_001156596 NM_001163125 NP_001156597 NM_001163130 NP_001156602 NM_145654 NP_663629 NR_027996 NR_027997 NR_027998 NR_027999 NR_028000 |
Function | May confer resistance to the antitumor agent cisplatin. Binds to DNA and RNA. {ECO:0000269|PubMed:15611051}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:17905820}. Cytoplasm {ECO:0000269|PubMed:17905820}. Nucleus, nucleolus {ECO:0000269|PubMed:17905820}. Note=Isoform 3 and isoform 10 are predominantly nuclear and nucleolar. After treatment with proteasomal inhibitors and mild heat-shock stress, isoform 1, isoform 3, isoform 5, isoform 7, isoform 8 and isoform 10 are relocalized to the nucleolus as dot-like or irregular subnuclear structures. Isoform 1 colocalized with nuclear promyelocytic leukemia (PML) and Cajal bodies (CB); this association with nuclear bodies is enhanced in response to proteotoxic stress. Isoform 3, but not isoform 1 and isoform 5, is relocalized in nucleolar caps during transcriptional arrest. |
Tissue Specificity | Expressed in testis. {ECO:0000269|PubMed:15611051}. |
RDM1 - MBS1277457 from MyBioSource
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RDM1 - MBS1273222 from MyBioSource
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Human RDM1 cDNA clone(NM_145654.3) - CDFG009047 from Creative Biomart
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Human RDM1 cDNA clone(NM_001034836.1) - CDFH016112 from Creative Biomart
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Human RDM1 cDNA clone(NM_001163121.1) - CDFH016113 from Creative Biomart
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Human RDM1 cDNA clone(NM_001163120.1) - CDFH016114 from Creative Biomart
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Human RDM1 cDNA clone(NM_001163122.1) - CDFH016115 from Creative Biomart
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Human RDM1 cDNA clone(NM_001163124.1) - CDFH016116 from Creative Biomart
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Human RDM1 cDNA clone(NM_001163130.1) - CDFH016117 from Creative Biomart
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Human RDM1 cDNA clone(NM_001163125.1) - CDFH016118 from Creative Biomart
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Human RDM1 ORF Clone(NM_001034836.1) - CDCL173489 from Creative Biomart
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Human RDM1 ORF Clone(NM_001034836.1) - CDCL173490 from Creative Biomart
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Human RDM1 ORF Clone(NM_145654.3) - CDCR318525 from Creative Biomart
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Human RDM1 ORF Clone(NM_145654.3) - CDCR318526 from Creative Biomart
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Human RDM1 ORF Clone(NM_145654.3) - CDCR318527 from Creative Biomart
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Human RDM1 ORF Clone(NM_001034836.1) - CDCR343275 from Creative Biomart
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Human RDM1 ORF Clone(NM_001034836.1) - CDCR343276 from Creative Biomart
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Human RDM1 ORF Clone(NM_001163120.1) - CDCR354307 from Creative Biomart
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Human RDM1 ORF Clone(NM_001163120.1) - CDCR354308 from Creative Biomart
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Human RDM1 ORF Clone(NM_001163121.1) - CDCR354309 from Creative Biomart
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Human RDM1 ORF Clone(NM_001163122.1) - CDCR354310 from Creative Biomart
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Human RDM1 ORF Clone(NM_001163122.1) - CDCR354311 from Creative Biomart
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Human RDM1 ORF Clone(NM_001163124.1) - CDCR354312 from Creative Biomart
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Human RDM1 ORF Clone(NM_001163124.1) - CDCR354313 from Creative Biomart
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Human RDM1 ORF Clone(NM_001163121.1) - CDCR354314 from Creative Biomart
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