| Gene Symbol |
CCDC28B
|
| Entrez Gene |
79140
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
coiled-coil domain containing 28B
|
| Other Description |
coiled-coil domain-containing protein 28B
|
| Swissprots |
Q8TBV8 Q9BUN5 A8K789
|
| Accessions |
EAX07563 EAX07564 Q9BUN5 AK092702 AK225113 AK291904 BAF84593 BC002462 BC022848 AAH22848 BM981930 DA899719 HQ448148 ADQ32629 XM_011542113 XP_011540415 NM_001301011 NP_001287940 NM_024296 NP_077272
|
| Function |
Involved in ciliogenesis. Regulates cilia length through its interaction with MAPKAP1/SIN1 but independently of mTORC2 complex. Modulates mTORC2 complex assembly and function, possibly enhances AKT1 phosphorylation. Does not seem to modulate assembly and function of mTORC1 complex. {ECO:0000269|PubMed:23015189, ECO:0000269|PubMed:23727834}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:16327777}. Note=It localizes near centrosomes and basal bodies.
|