Gene Symbol | CCDC28B |
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Entrez Gene | 79140 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | coiled-coil domain containing 28B |
Other Description | coiled-coil domain-containing protein 28B |
Swissprots | Q8TBV8 Q9BUN5 A8K789 |
Accessions | EAX07563 EAX07564 Q9BUN5 AK092702 AK225113 AK291904 BAF84593 BC002462 BC022848 AAH22848 BM981930 DA899719 HQ448148 ADQ32629 XM_011542113 XP_011540415 NM_001301011 NP_001287940 NM_024296 NP_077272 |
Function | Involved in ciliogenesis. Regulates cilia length through its interaction with MAPKAP1/SIN1 but independently of mTORC2 complex. Modulates mTORC2 complex assembly and function, possibly enhances AKT1 phosphorylation. Does not seem to modulate assembly and function of mTORC1 complex. {ECO:0000269|PubMed:23015189, ECO:0000269|PubMed:23727834}. |
Subcellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:16327777}. Note=It localizes near centrosomes and basal bodies. |
MGC1203 CRISPR/Cas9 KO Plasmid (h) - sc-413139 from Santa Cruz Biotechnology
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MGC1203 HDR Plasmid (h) - sc-413139-HDR from Santa Cruz Biotechnology
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MGC1203 Double Nickase Plasmid (h) - sc-413139-NIC from Santa Cruz Biotechnology
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MGC1203 Double Nickase Plasmid (h2) - sc-413139-NIC-2 from Santa Cruz Biotechnology
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MGC1203 CRISPR Activation Plasmid (h) - sc-413139-ACT from Santa Cruz Biotechnology
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MGC1203 CRISPR Activation Plasmid (h2) - sc-413139-ACT-2 from Santa Cruz Biotechnology
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MGC1203 Lentiviral Activation Particles (h) - sc-413139-LAC from Santa Cruz Biotechnology
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MGC1203 Lentiviral Activation Particles (h2) - sc-413139-LAC-2 from Santa Cruz Biotechnology
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MGC1203 siRNA (h) - sc-88722 from Santa Cruz Biotechnology
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MGC1203 shRNA Plasmid (h) - sc-88722-SH from Santa Cruz Biotechnology
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MGC1203 shRNA (h) Lentiviral Particles - sc-88722-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU082341 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5516 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5516 from Sigma-Aldrich
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CCDC28B siRNA (Human) - CRJ2323 from Cohesion Biosciences
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CCDC28B - MBS8219971 from MyBioSource
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shRNA set against Human CCDC28B (NM_024296.3) - SHH256517 from Creative biogene
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shRNA set against Human CCDC28B(NM_024296.3) - SHG147889 from Creative biogene
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CCDC28B shRNA Plasmid (Human) - CHJ2323 from Cohesion Biosciences
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CCDC28B miRNA 3'UTR clone - MiUTR1H-01743 from Creative biogene
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