CA2

Gene Symbol	CA2
Entrez Gene	760
Alt Symbol	CA-II, CAC, CAII, Car2, HEL-76
Species	Human
Gene Type	protein-coding
Description	carbonic anhydrase II
Other Description	carbonate dehydratase II|carbonic anhydrase 2|carbonic anhydrase B|carbonic anhydrase C|carbonic dehydratase|epididymis luminal protein 76
Swissprots	Q96ET9 P00918 Q6FI12 B2R7G8
Accessions	AAA51909 CAA27012 EAW87136 P00918 AF015039 AK123309 AK312978 BAG35815 BC011949 AAH11949 BC035424 CD013933 CR536526 CAG38763 CR541875 CAG46673 DA431650 DQ891320 ABM82246 DQ894504 ABM85430 FJ224289 ACI45981 J03037 AAA51908 M36532 AAA51911 S69526 AAB30170 Y00339 CAA68426 NM_000067 NP_000058 NM_001293675 NP_001280604
Function	Essential for bone resorption and osteoclast differentiation (By similarity). Reversible hydration of carbon dioxide. Can hydrate cyanamide to urea. Involved in the regulation of fluid secretion into the anterior chamber of the eye. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton-coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6. {ECO:0000250, ECO:0000269|PubMed:10550681, ECO:0000269|PubMed:11831900, ECO:0000269|PubMed:15990874}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:15990874}. Cell membrane {ECO:0000269|PubMed:15990874}. Note=Colocalized with SLC26A6 at the surface of the cell membrane in order to form a bicarbonate transport metabolon. Displaced from the cytosolic surface of the cell membrane by PKC in phorbol myristate acetate (PMA)-induced cells.
Top Pathways	Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Collecting duct acid secretion, Gastric acid secretion, Pancreatic secretion

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CA2 / Carbonic Anhydrase II ELISA Kit (Sandwich ELISA) - LS-F4349 from LifeSpan Bioscience Category ELISA Kit Prices $580.00 Sizes 1 plate Sensitivity 0.156 ng/ml Range 0.156-10 ng/ml

Chicken CA2 / Carbonic Anhydrase II ELISA Kit (Sandwich ELISA) - LS-F5420 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 0.59 ng/ml Range 0.156-10 ng/ml

Rhesus monkey CA2 / Carbonic Anhydrase II ELISA Kit (Sandwich ELISA) - LS-F8551 from LifeSpan Bioscience Category ELISA Kit Prices $740.00 Sizes 1 plate Sensitivity 1.22 ng/ml Range 0.156-10 ng/ml

Chicken CA2 / Carbonic Anhydrase II ELISA Kit (Sandwich ELISA) - LS-F10989 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 3.12 Range 0.156-10 ng/ml

Human Carbonic Anhydrase 2 ELISA Kit - abx052917 from Abbexa Category ELISA Kit Sensitivity 8 pg/ml Range 38 pg/ml - 2000 pg/ml

Human Carbonic Anhydrase II ELISA Kit - abx150928 from Abbexa Category ELISA Kit Sensitivity 1.34 ng/ml Range 3.125 ng/ml - 200 ng/ml

Carbonic Anhydrase II, CA2, Human, ELISA Kit - E-EL-H0640 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 1.875 Range 3.125-200ng/mL

Carbonic anhydrase 2, CA-2, Human, ELISA Kit - CSB-E08823h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.08 ng/ml Range 0.31 ng/ml-20 ng/ml

Carbonic anhydrase 2, CA2, Human, ELISA Kit - E0782h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 1.56-100 U/ml

Carbonic Anhydrase II (CA2), Human, ELISA Kit - SEA782Hu from ARP American Research Products Category ELISA Kit Prices $580.00 Sizes 96 t Sensitivity 1.19ng/mL Range 3.12-200ng/mL

Carbonic Anhydrase II, Human, ELISA Kit - E01C0621 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0ng/ml Range 2.5-50ng/mL,

Carnitine-acylcarnitine translocase, CACT, Human, ELISA Kit - CSB-E13546h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Carbonic Anhydrase 2, CA2, Mouse, ELISA Kit - E-EL-M0229 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.938 Range 1.563-100ng/mL

Carbonic Anhydrase II, CA2, Rat, ELISA Kit - E-EL-R0147 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 1.688 Range 2.813-180ng/mL

Carbonic Anhydrase II, CA2, Rabbit, ELISA Kit - E-EL-RB1059 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Carbonic Anhydrase II, CA2, Chicken, ELISA Kit - E-EL-Ch0777 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t Sensitivity 0.938 Range 1.563-100ng/mL

Carbonic Anhydrase II, CA2, Porcine, ELISA Kit - E-EL-P0549 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Carbonic Anhydrase II, CA2, Guinea Pig, ELISA Kit - E-EL-GP0420 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t

Carbonic Anhydrase II, CA2, Monkey, ELISA Kit - E-EL-MK1565 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 1.875 Range 3.125-200ng/mL

Human CA2 ELISA Kit - HC0628 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine CA2 ELISA Kit - AC0628 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Carbonic Anhydrase II, ELISA Kit - MBS731855 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carbonic Anhydrase II, ELISA Kit - MBS736236 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 1.0 ng/mL.

Carbonic Anhydrase II, ELISA Kit - MBS720381 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,850.00, $5,340.00 Sizes 48 -strip-wells- (Competitive), 96 -strip-wells- (Competitive), 5x96-strip-wells- (Competitive), 10x96-strip-wells- (Competitive) Sensitivity 1.0 ng/mL.

Carbonic Anhydrase II (CA2), ELISA Kit - MBS267779 from MyBioSource Category ELISA Kit Prices $275.00, $420.00, $1,615.00, $2,880.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.5U/L. Range 100 U/L-1.56 U/L

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