Gene Symbol |
ITGB5
|
Entrez Gene |
3693
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
integrin, beta 5
|
Other Description |
integrin beta-5
|
Swissprots |
B0LPF8 B2RD70 P18084
|
Accessions |
ABY87537 AGC09593 EAW79405 EAW79406 P18084 AK054968 AK130168 AK309551 AK315429 BAG37817 BC006541 AAH06541 BQ007769 BX095583 DQ892778 ABM83704 DQ896025 ABM87024 J05633 AAA59183 M35011 AAA52707 X53002 CAA37188 XM_005247436 XP_005247493 XM_006713630 XP_006713693 NM_002213 NP_002204
|
Function |
Integrin alpha-V/beta-5 (ITGAV:ITGB5) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.
|
Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
Top Pathways |
Dilated cardiomyopathy, Proteoglycans in cancer, PI3K-Akt signaling pathway, Phagosome, Focal adhesion
|