Gene Symbol | ITGB5 |
---|---|
Entrez Gene | 3693 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | integrin, beta 5 |
Other Description | integrin beta-5 |
Swissprots | B0LPF8 B2RD70 P18084 |
Accessions | ABY87537 AGC09593 EAW79405 EAW79406 P18084 AK054968 AK130168 AK309551 AK315429 BAG37817 BC006541 AAH06541 BQ007769 BX095583 DQ892778 ABM83704 DQ896025 ABM87024 J05633 AAA59183 M35011 AAA52707 X53002 CAA37188 XM_005247436 XP_005247493 XM_006713630 XP_006713693 NM_002213 NP_002204 |
Function | Integrin alpha-V/beta-5 (ITGAV:ITGB5) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | Dilated cardiomyopathy, Proteoglycans in cancer, PI3K-Akt signaling pathway, Phagosome, Focal adhesion |