RPL13A

Gene Symbol RPL13A
Entrez Gene 23521
Alt Symbol L13A, TSTA1
Species Human
Gene Type protein-coding
Description ribosomal protein L13a
Other Description 23 kDa highly basic protein|60S ribosomal protein L13a|tissue specific transplantation antigen 1
Swissprots P40429 A8K505
Accessions BAA88214 EAW52495 EAW52496 P40429 AB082924 BAC16800 AK056837 AK130605 AK222747 BAD96467 AK291120 BAF83809 AK297859 BAG60190 BC000514 AAH00514 BC000847 BC001675 AAH01675 BC001836 AAH01836 BC004900 AAH04900 BC013230 BC032107 BC062537 AAH62537 BC065236 AAH65236 BC070223 AAH70223 BC071929 AAH71929 BC105605 AAI05606 BG536330 BQ069994 EU831455 ACE87142 EU831542 ACE86461 HQ447707 ADQ32192 X56932 CAA40254 NM_001270491 NP_001257420 NM_012423 NP_036555 NR_073024
Function Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex. Involved in methylation of rRNA. {ECO:0000269|PubMed:14567916, ECO:0000269|PubMed:17218275, ECO:0000269|PubMed:17921318, ECO:0000269|PubMed:23071094}.
Subcellular Location Cytoplasm {ECO:0000305|PubMed:14567916}.
Top Pathways Ribosome

Human RPL13A full length protein - ab161670 from Abcam

Category Protein
Source Wheat germ
Species Human
ab161670 on a 12.5% SDS-PAGE stained with Coomassie Blue.

RPL13A Antibody Blocking Peptide - LS-E21414 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

RPL13A Antibody Blocking Peptide - LS-E6539 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human RPL13A Protein - H00023521-P01 from Novus Biologicals

Category Protein
Prices $319.00
Sizes 2 µg
Source Wheat Germ
Species Human

RPL13A Blocking Peptide - 33R-3724 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

RPL13A - H00023521-P01 from Acris Antibodies

Category Protein
Prices $310.00
Sizes 2 µg
Species Human

RPL13A fusion protein - ag6321 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

RPL13A fusion protein - Ag6212 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Human RPL13A, His-tagged - RPL13A-2376H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Ribosomal Protein L13A (RPL13A) - RPQ321Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Recombinant Ribosomal Protein L13A (RPL13A) - RPQ321Hu01 from Cloud-clone

Category Protein
Source E.coli
Species Human

Recombinant Human 60S ribosomal protein L13a(RPL13A) - CSB-YP020130HU CSB-EP020130HU CSB-BP020130HU CSB-MP020130HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

RPL13A Recombinant Protein Antigen - NBP1-92345PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

RPL13A-Antibody-C-term-Blocking-Peptide - BP4932b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

RPL13A Peptide, Human - M34GP13503H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human
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