RPL13A

Gene Symbol RPL13A
Entrez Gene 23521
Alt Symbol L13A, TSTA1
Species Human
Gene Type protein-coding
Description ribosomal protein L13a
Other Description 23 kDa highly basic protein|60S ribosomal protein L13a|tissue specific transplantation antigen 1
Swissprots P40429 A8K505
Accessions BAA88214 EAW52495 EAW52496 P40429 AB082924 BAC16800 AK056837 AK130605 AK222747 BAD96467 AK291120 BAF83809 AK297859 BAG60190 BC000514 AAH00514 BC000847 BC001675 AAH01675 BC001836 AAH01836 BC004900 AAH04900 BC013230 BC032107 BC062537 AAH62537 BC065236 AAH65236 BC070223 AAH70223 BC071929 AAH71929 BC105605 AAI05606 BG536330 BQ069994 EU831455 ACE87142 EU831542 ACE86461 HQ447707 ADQ32192 X56932 CAA40254 NM_001270491 NP_001257420 NM_012423 NP_036555 NR_073024
Function Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex. Involved in methylation of rRNA. {ECO:0000269|PubMed:14567916, ECO:0000269|PubMed:17218275, ECO:0000269|PubMed:17921318, ECO:0000269|PubMed:23071094}.
Subcellular Location Cytoplasm {ECO:0000305|PubMed:14567916}.
Top Pathways Ribosome

Ribosomal Protein L13A CRISPR/Cas9 KO Plasmid (h) - sc-403494 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ribosomal Protein L13A HDR Plasmid (h) - sc-403494-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ribosomal Protein L13A Double Nickase Plasmid (h) - sc-403494-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ribosomal Protein L13A Double Nickase Plasmid (h2) - sc-403494-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ribosomal Protein L13A CRISPR Activation Plasmid (h) - sc-403494-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ribosomal Protein L13A CRISPR Activation Plasmid (h2) - sc-403494-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ribosomal Protein L13A Lentiviral Activation Particles (h) - sc-403494-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ribosomal Protein L13A Lentiviral Activation Particles (h2) - sc-403494-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Ribosomal Protein L13A siRNA (h) - sc-97893 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Ribosomal Protein L13A shRNA Plasmid (h) - sc-97893-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Ribosomal Protein L13A shRNA (h) Lentiviral Particles - sc-97893-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU117571 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

MISSION® esiRNA - EHU148451 from Sigma-Aldrich

Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN18539 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18539 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04772 from Sigma-Aldrich

Category miRNA

RPL13A siRNA (Human) - CRH8327 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RPL13A - MBS8208576 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human RPL13A (NM_012423.3) - SHH398136 from Creative biogene

Category siRNA
Species Reactivities Human

Human RPL13A siRNA - orb268829 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

RPL13A shRNA Plasmid (Human) - CHH8327 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

RPL13A miRNA 3'UTR clone - MiUTR1H-08975 from Creative biogene

Species Reactivities Human

RPL13A miRNA 3'UTR clone - MiUTR3H-15934 from Creative biogene

Species Reactivities Human
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