EIF3CL

Gene Symbol EIF3CL
Entrez Gene 728689
Alt Symbol -
Species Human
Gene Type protein-coding
Description eukaryotic translation initiation factor 3, subunit C-like
Other Description eIF3 p110|eIF3c|eukaryotic translation initiation factor 3 subunit 8|eukaryotic translation initiation factor 3 subunit C|eukaryotic translation initiation factor 3 subunit C-like protein|eukaryotic translation initiation factor 3, subunit 8, 110kDa-like
Swissprots B5ME19
Accessions B5ME19 XM_005255535 XP_005255592 NM_001099661 NP_001093131
Function Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}.
Top Pathways RNA transport

eIF3 p110 CRISPR/Cas9 KO Plasmid (h) - sc-416227 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF3 p110 HDR Plasmid (h) - sc-416227-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF3 p110 Double Nickase Plasmid (h) - sc-416227-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF3 p110 Double Nickase Plasmid (h2) - sc-416227-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF3 p110 CRISPR Activation Plasmid (h) - sc-416227-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF3 p110 CRISPR Activation Plasmid (h2) - sc-416227-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF3 p110 Lentiviral Activation Particles (h) - sc-416227-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

eIF3 p110 Lentiviral Activation Particles (h2) - sc-416227-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN7759 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7759 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

EIF3CL siRNA (Human) - CRJ8688 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

EIF3CL - MBS8223624 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human EIF3CL (NM_001099661.1) - SHH284457 from Creative biogene

Category siRNA
Species Reactivities Human

EIF3CL shRNA Plasmid (Human) - CHJ8688 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

EIF3CL miRNA 3'UTR clone - MiUTR3H-14724 from Creative biogene

Species Reactivities Human
Search more