| Gene Symbol |
NDC1
|
| Entrez Gene |
55706
|
| Alt Symbol |
NET3, TMEM48
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
NDC1 transmembrane nucleoporin
|
| Other Description |
nuclear division cycle 1 homolog|nucleoporin NDC1|transmembrane protein 48
|
| Swissprots |
Q9H9T6 B4DHA3 Q9NSG3 Q8NB76 B4DQQ5 Q9NVZ7 Q9NSG4 G3XA81 Q9BTX1
|
| Accessions |
EAX06731 EAX06732 EAX06733 Q9BTX1 AK001269 BAA91592 AK001593 AK022618 BAB14135 AK025450 AK091439 BAC03665 AK295000 BAG58064 AK298909 BAG61017 AK302910 BAG64078 AL354612 CAB89725 AL354613 CAB89726 BC003082 AAH03082 BM554303 BX648031 DC413103 DQ141696 AAZ73087 XM_006710762 XP_006710825 XM_011541766 XP_011540068 NM_001168551 NP_001162023 NM_018087 NP_060557 NR_033142
|
| Function |
Component of the nuclear pore complex (NPC), which plays a key role in de novo assembly and insertion of NPC in the nuclear envelope. Required for NPC and nuclear envelope assembly, possibly by forming a link between the nuclear envelope membrane and soluble nucleoporins, thereby anchoring the NPC in the membrane. {ECO:0000269|PubMed:16600873, ECO:0000269|PubMed:16702233}.
|
| Subcellular Location |
Nucleus, nuclear pore complex. Nucleus membrane; Multi-pass membrane protein. Note=Central core structure of the nuclear pore complex.
|
| Top Pathways |
RNA transport
|
![Western Blot: TMEM48 Overexpression Lysate (Adult Normal) [NBP2-06877] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TMEM48.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1691_TMEM48%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06877-img0001.jpg)