Gene Symbol | CLCN6 |
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Entrez Gene | 1185 |
Alt Symbol | CLC-6 |
Species | Human |
Gene Type | protein-coding |
Description | chloride channel, voltage-sensitive 6 |
Other Description | chloride transport protein 6 |
Swissprots | Q5SNX1 Q99428 Q5SNW3 Q99429 F8W9R3 O60820 B4DGT7 Q5SNX3 P51797 O60819 Q99427 O60821 P78520 Q17R81 P78521 O60818 A8K1T4 Q5SNX2 Q5SNW2 |
Accessions | AAB69287 AAN40862 CAA67835 EAW71710 EAW71711 EAW71712 EAW71713 EAW71714 EAW71715 EAW71716 P51797 AK289999 BAF82688 AK294764 BAG57898 AK307098 BC050457 BC117420 AAI17421 BC117424 AAI17425 BC143844 D28475 BAA05836 DA229615 DA935587 HQ258635 ADR83387 R20538 X83378 CAA58292 X96391 CAA65255 X99473 CAA67836 X99474 CAA67837 X99475 CAA67838 NM_001256959 NP_001243888 NM_001286 NP_001277 NR_046428 NM_021735 NM_021736 NM_021737 |
Function | Chloride transport protein, initially identified as voltage-gated chloride channel. The presence of the conserved gating glutamate residues suggests that is functions as antiporter. |
Subcellular Location | Endosome membrane {ECO:0000269|PubMed:17534424}; Multi-pass membrane protein {ECO:0000269|PubMed:17534424}. Note=Detected in detergent- resistant lipid rafts. |
Tissue Specificity | Testis, ovary, small intestine, brain and skeletal muscle. Low level expression in aortic and coronary vascular smooth muscle cells, and aortic endothelial cells. Isoform 3 is only detected in kidney. {ECO:0000269|PubMed:10198195, ECO:0000269|PubMed:8543009, ECO:0000269|PubMed:9224655}. |
CLC-6 (I-15) - sc-16440 from Santa Cruz Biotechnology
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CLC-6 (N-20) - sc-16439 from Santa Cruz Biotechnology
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Anti-CLCN6 antibody - ab75048 from Abcam
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Anti-CLCN6 antibody - C-terminal - ab192928 from Abcam
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Anti-CLCN6 Antibody (C-Terminus) - LS-C6135 from LifeSpan Bioscience
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Anti-CLCN6 Antibody (aa215-264) - LS-C30849 from LifeSpan Bioscience
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Anti-CLCN6 Antibody (C-Terminus) - LS-C345633 from LifeSpan Bioscience
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Anti-CLCN6 Antibody (aa611-660) - LS-C119847 from LifeSpan Bioscience
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Anti-CLCN6 Antibody (Lys649) - LS-C177361 from LifeSpan Bioscience
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Anti-CLCN6 Antibody (clone 2H2) - LS-C196931 from LifeSpan Bioscience
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CLCN6 Antibody - NBP1-00756 from Novus Biologicals
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CLCN6 Antibody - NBP1-85583 from Novus Biologicals
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CLCN6 Antibody (2H2) - H00001185-M05 from Novus Biologicals
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Monoclonal Anti-CLCN6, (C-terminal) antibody produced in mouse - SAB1402726 from Sigma-Aldrich
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Anti-CLCN6 antibody produced in rabbit - HPA032097 from Sigma-Aldrich
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Anti-CLCN6 antibody produced in rabbit - AV35334 from Sigma-Aldrich
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Anti-CLCN6 antibody produced in rabbit - SAB4500283 from Sigma-Aldrich
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CLCN6 antibody - C-terminal region (ARP35334_T100) - ARP35334_T100 from Aviva Systems Biology
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CLCN6 Antibody - C-terminal region (ARP73793_P050) - ARP73793_P050 from Aviva Systems Biology
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CLCN6 antibody, C-term - GTX47658 from GeneTex
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CLCN6 Antibody (OAAF07924) - OAAF07924 from Aviva Systems Biology
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CLCN6 antibody - 70R-1521 from Fitzgerald
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Anti -CLC-6 (Chloride transport Protein 6, Chloride Channel Protein 6, ClC-6, CLCN6,KIAA0046) - 221742 from USBiological Life Science
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Anti -CLCN6 (Chloride Transport Protein 6, Chloride Channel Protein 6, ClC-6, KIAA0046) - 125033 from USBiological Life Science
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Anti -CLCN6 (Chloride Transport Protein 6, Chloride Channel Protein 6, ClC-6, KIAA0046)(AP) - 125033-AP from USBiological Life Science
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