| Gene Symbol |
NDUFS3
|
| Entrez Gene |
4722
|
| Alt Symbol |
CI-30
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
|
| Other Description |
CI-30kD|NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial|NADH dehydrogenase-ubiquinone 30 kDa subunit|NADH-ubiquinone oxidoreductase 30 kDa subunit|complex I 30kDa subunit|complex I-30kD
|
| Swissprots |
O75489 B2R9J1 Q9UNQ8 B4DFM8
|
| Accessions |
AAG17541 EAW67895 EAW67896 EAW67897 O75489 AA477836 AF067139 AAC27451 AF100743 AAD40386 AK223255 BAD96975 AK294167 BAG57489 AK313802 BAG36538 AL135819 CAB63881 BC000617 AAH00617 DA893277 DQ891934 ABM82860 DQ895121 ABM86047 NM_004551 NP_004542
|
| Function |
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Mitochondrion inner membrane.
|
| Top Pathways |
Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation
|