Gene Symbol | NDUFS3 |
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Entrez Gene | 4722 |
Alt Symbol | CI-30 |
Species | Human |
Gene Type | protein-coding |
Description | NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) |
Other Description | CI-30kD|NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial|NADH dehydrogenase-ubiquinone 30 kDa subunit|NADH-ubiquinone oxidoreductase 30 kDa subunit|complex I 30kDa subunit|complex I-30kD |
Swissprots | O75489 B2R9J1 Q9UNQ8 B4DFM8 |
Accessions | AAG17541 EAW67895 EAW67896 EAW67897 O75489 AA477836 AF067139 AAC27451 AF100743 AAD40386 AK223255 BAD96975 AK294167 BAG57489 AK313802 BAG36538 AL135819 CAB63881 BC000617 AAH00617 DA893277 DQ891934 ABM82860 DQ895121 ABM86047 NM_004551 NP_004542 |
Function | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250}. |
Subcellular Location | Mitochondrion inner membrane. |
Top Pathways | Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
NDUFS3 CRISPR/Cas9 KO Plasmid (h) - sc-404639 from Santa Cruz Biotechnology
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NDUFS3 HDR Plasmid (h) - sc-404639-HDR from Santa Cruz Biotechnology
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NDUFS3 Double Nickase Plasmid (h) - sc-404639-NIC from Santa Cruz Biotechnology
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NDUFS3 Double Nickase Plasmid (h2) - sc-404639-NIC-2 from Santa Cruz Biotechnology
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NDUFS3 CRISPR Activation Plasmid (h) - sc-404639-ACT from Santa Cruz Biotechnology
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NDUFS3 CRISPR Activation Plasmid (h2) - sc-404639-ACT-2 from Santa Cruz Biotechnology
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NDUFS3 Lentiviral Activation Particles (h) - sc-404639-LAC from Santa Cruz Biotechnology
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NDUFS3 Lentiviral Activation Particles (h2) - sc-404639-LAC-2 from Santa Cruz Biotechnology
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NDUFS3 siRNA (h) - sc-75890 from Santa Cruz Biotechnology
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NDUFS3 shRNA Plasmid (h) - sc-75890-SH from Santa Cruz Biotechnology
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NDUFS3 shRNA (h) Lentiviral Particles - sc-75890-V from Santa Cruz Biotechnology
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NDUFS3 RNAi - H00004722-R01V from Novus Biologicals
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NDUFS3 RNAi - H00004722-R01 from Novus Biologicals
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MISSION® esiRNA - EHU220521 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15168 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15168 from Sigma-Aldrich
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NDUFS3 siRNA (Human) - CRH3135 from Cohesion Biosciences
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NDUFS3 CRISPR/Cas9 KO Plasmid (h2) - sc-404639-KO-2 from Santa Cruz Biotechnology
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NDUFS3 HDR Plasmid (h2) - sc-404639-HDR-2 from Santa Cruz Biotechnology
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NDUFS3 shRNA Plasmid (Human) - CHH3135 from Cohesion Biosciences
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