Gene Symbol |
KLRC3
|
Entrez Gene |
3823
|
Alt Symbol |
NKG2-E, NKG2E
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
killer cell lectin-like receptor subfamily C, member 3
|
Other Description |
NK cell receptor E|NKG2-E type II integral membrane protein|NKG2-E-activating NK receptor
|
Swissprots |
Q07444 Q9UP04 Q96RL0 Q8WXA4
|
Accessions |
AAC17490 AAG26339 CAA04923 EAW96184 EAW96185 EAW96186 Q07444 AF078550 AAD46108 AF350016 AAK83803 AF350017 AAK83804 AF461157 AAL65232 AK307860 AK311162 BC160065 AAI60065 L14542 AAA16833 NM_002261 NP_002252 NM_007333 NP_031359
|
Function |
Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
|
Subcellular Location |
Membrane; Single-pass type II membrane protein.
|
Tissue Specificity |
Natural killer cells.
|
Top Pathways |
Natural killer cell mediated cytotoxicity, Antigen processing and presentation
|