Gene Symbol | KLRC3 |
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Entrez Gene | 3823 |
Alt Symbol | NKG2-E, NKG2E |
Species | Human |
Gene Type | protein-coding |
Description | killer cell lectin-like receptor subfamily C, member 3 |
Other Description | NK cell receptor E|NKG2-E type II integral membrane protein|NKG2-E-activating NK receptor |
Swissprots | Q07444 Q9UP04 Q96RL0 Q8WXA4 |
Accessions | AAC17490 AAG26339 CAA04923 EAW96184 EAW96185 EAW96186 Q07444 AF078550 AAD46108 AF350016 AAK83803 AF350017 AAK83804 AF461157 AAL65232 AK307860 AK311162 BC160065 AAI60065 L14542 AAA16833 NM_002261 NP_002252 NM_007333 NP_031359 |
Function | Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. |
Subcellular Location | Membrane; Single-pass type II membrane protein. |
Tissue Specificity | Natural killer cells. |
Top Pathways | Natural killer cell mediated cytotoxicity, Antigen processing and presentation |
NKG2-E CRISPR/Cas9 KO Plasmid (h) - sc-416263 from Santa Cruz Biotechnology
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NKG2-E HDR Plasmid (h) - sc-416263-HDR from Santa Cruz Biotechnology
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NKG2-E Double Nickase Plasmid (h) - sc-416263-NIC from Santa Cruz Biotechnology
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NKG2-E Double Nickase Plasmid (h2) - sc-416263-NIC-2 from Santa Cruz Biotechnology
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NKG2-E CRISPR Activation Plasmid (h) - sc-416263-ACT from Santa Cruz Biotechnology
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NKG2-E CRISPR Activation Plasmid (h2) - sc-416263-ACT-2 from Santa Cruz Biotechnology
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NKG2-E Lentiviral Activation Particles (h) - sc-416263-LAC from Santa Cruz Biotechnology
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NKG2-E Lentiviral Activation Particles (h2) - sc-416263-LAC-2 from Santa Cruz Biotechnology
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NKG2E/KLRC3 RNAi - H00003823-R03 from Novus Biologicals
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NKG2E/KLRC3 RNAi - H00003823-R04 from Novus Biologicals
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MISSION® esiRNA - EHU160921 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11323 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11323 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01698 from Sigma-Aldrich
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KLRC3 siRNA (Human) - CRH2591 from Cohesion Biosciences
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shRNA set against Human KLRC3 (NM_002261.2) - SHH326827 from Creative biogene
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shRNA set against Human KLRC3(NM_002261.2) - SHL203580 from Creative biogene
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shRNA set against Human KLRC3(NM_007333.2) - SHL203598 from Creative biogene
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Human KLRC3 siRNA - orb263093 from Biorbyt
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KLRC3 shRNA Plasmid (Human) - CHH2591 from Cohesion Biosciences
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KLRC3 miRNA 3'UTR clone - MiUTR1H-05413 from Creative biogene
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KLRC3 miRNA 3'UTR clone - MiUTR1H-05414 from Creative biogene
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