| Gene Symbol |
SYNC
|
| Entrez Gene |
81493
|
| Alt Symbol |
SYNC1, SYNCOILIN
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
syncoilin, intermediate filament protein
|
| Other Description |
intermediate filament protein syncoilin|syncoilin|syncoilin intermediate filament 1|syncoilin, intermediate filament 1|syncoilin-1
|
| Swissprots |
C9IY41 Q9H7C4 B4DNK8 B4DY58
|
| Accessions |
EAX07511 EAX07512 Q9H7C4 AA376455 AI752560 AK024707 BAB14970 AK297958 BAG60270 AK302275 BAG63620 BC119700 AAI19701 BC119701 AAI19702 DC355889 DC398945 DN991289 NM_001161708 NP_001155180 NM_030786 NP_110413
|
| Function |
Atypical type III intermediate filament (IF) protein that may play a supportive role in the efficient coupling of mechanical stress between the myofibril and fiber exterior. May facilitate lateral force transmission during skeletal muscle contraction. Does not form homofilaments nor heterofilaments with other IF proteins. {ECO:0000250|UniProtKB:Q9EPM5}.
|
| Subcellular Location |
Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q9EPM5}. Note=In skeletal muscle, colocalizes with DES and DTNA, and is localized at the myotendinous and neuromuscular junctions, sarcolemma and Z-lines. In myotubes, detected in a punctate cytoplasmic pattern (By similarity). {ECO:0000250|UniProtKB:Q9EPM5}.
|