GPX4

Gene Symbol	GPX4
Entrez Gene	2879
Alt Symbol	GPx-4, GSHPx-4, MCSP, PHGPx, snGPx, snPHGPx
Species	Human
Gene Type	protein-coding
Description	glutathione peroxidase 4
Other Description	phospholipid hydroperoxidase|phospholipid hydroperoxide glutathione peroxidase, mitochondrial|sperm nucleus glutathione peroxidase
Swissprots	P36969 O43381 Q9UPK2 Q6PJ59
Accessions	AAC03239 AAC28920 AAC32261 AAP72965 EAW69543 EAW69544 EAW69545 EAW69546 P36969 AI274351 AK225859 AL558552 BC010157 AAH10157 BC011836 AAH11836 BC021567 AAH21567 BC022071 AAH22071 BC032695 AAH32695 BC039849 AAH39849 BC046163 AAH46163 BC058329 BI561548 BM764133 BQ648717 CF127510 HY049693 X71973 CAA50793 NM_001039847 NP_001034936 NM_001039848 NP_001034937 NM_002085 NP_002076
Function	Protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility. Could play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage (By similarity). {ECO:0000250}.
Subcellular Location	Isoform Mitochondrial: Mitochondrion.
Tissue Specificity	Present primarily in testis.
Top Pathways	Glutathione metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Glutathione Peroxidase 4 full length protein - ab109348 from Abcam Category Protein Source E. coli Species Human

Human Glutathione Peroxidase 4 full length protein - ab82660 from Abcam Category Protein Source E. coli Species Human

Human Glutathione Peroxidase 4 peptide - ab41785 from Abcam Category Peptide

Human Glutathione Peroxidase 4 peptide - ab41786 from Abcam Category Peptide

GPX4 / MCSP Antibody Blocking Peptide - LS-E21392 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GPX4 / MCSP Antibody Blocking Peptide - LS-E26129 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Glutathione Peroxidase 4/GPX4 Protein - P4548 from Novus Biologicals Category Protein Prices $549.00 Sizes 500 µg Source E. coli Species Human

GPX4 (Isoform a and c) blocking peptide - GTX89281-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

Glutathione Peroxidase 4 protein - 30R-2998 from Fitzgerald Category Protein Prices $265.00 Sizes 500 µg Source E.coli

GPX4 Blocking Peptide - 33R-7765 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Peroxiredoxin 6 protein (His tag) - 80R-1174 from Fitzgerald Category Protein Prices $255.00 Sizes 100 µg Source E.coli

Human GPX4 Protein - abx066827 from Abbexa Category Protein Source E.coli Species Human

Glutathione Peroxidase 4 Peptide - AC21-0959-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Glutathione peroxidase 4 / GPX4 - P4548 from Acris Antibodies Category Protein Prices $430.00 Sizes 500 µg Species Human

Glutathione Peroxidase 4 (GPX4), Human - 20-8631 from ARP American Research Products Category Protein Prices $517.00 Sizes 50 µg Source E.coli Species Human

GPX4 Peptide - 45-700P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

GPX4 fusion protein - Ag5809 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

GPX4 fusion protein - ag14632 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human GPX4, His-tagged - GPX4-29076TH from Creative Biomart Category Protein Source E. coli

Recombinant Human GPX4 Protein - GPX4-29080TH from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human GPX4, GST-tagged - GPX4-13510H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Glutathione Peroxidase 4 (GPX4) - RPC994Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

GPX4 - pro10215 from Covalab Category Protein Source Escherichia coli Species Human

Recombinant Human Phospholipid hydroperoxide glutathione peroxidase, mitochondri - CSB-YP009869HU CSB-EP009869HU CSB-BP009869HU CSB-MP009869HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Glutathione Peroxidase 4 (GPX4) - RPU141653 from Biomatik Category Protein Prices $246.40, $492.80, $739.20 Sizes 10 µg, 50 µg, 100 µg Source E.coli Species Human

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