| Gene Symbol |
NIPA1
|
| Entrez Gene |
123606
|
| Alt Symbol |
FSP3, SPG6
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
non imprinted in Prader-Willi/Angelman syndrome 1
|
| Other Description |
magnesium transporter NIPA1|non-imprinted in Prader-Willi/Angelman syndrome 1|non-imprinted in Prader-Willi/Angelman syndrome region protein 1|spastic paraplegia 6 protein
|
| Swissprots |
Q7KZB0 Q5HYA9 B2RA76 Q7RTP0 Q86XW4
|
| Accessions |
CAH05585 CCO13782 EAW65549 EAW65550 EAW65551 Q7RTP0 AB089319 BAC67707 AK057846 AK314073 BAG36773 BC025678 AAH25678 BC103705 AAI03706 BC156247 AAI56248 BC172484 AAI72484 BK001020 DAA01477 BX648722 CAI45979 DQ891252 ABM82178 DQ894438 ABM85364 NM_001142275 NP_001135747 NM_144599 NP_653200
|
| Function |
Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Early endosome {ECO:0000250}. Note=Recruited to the cell membrane in response to low extracellular magnesium. {ECO:0000250}.
|
| Tissue Specificity |
Widely expressed with highest levels in neuronal tissues. {ECO:0000269|PubMed:14508710}.
|