| Gene Symbol |
IBSP
|
| Entrez Gene |
3381
|
| Alt Symbol |
BNSP, BSP, BSP-II, SP-II
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
integrin-binding sialoprotein
|
| Other Description |
BSP II|bone sialoprotein 2|bone sialoprotein II|cell-binding sialoprotein
|
| Swissprots |
P21815
|
| Accessions |
AAA60549 AAC37560 CAI61689 EAX05998 EAX05999 EAX06000 P21815 AA452255 AI751848 BC111920 AAI11921 BQ573754 DV462680 J05213 AAC95490 NM_004967 NP_004958
|
| Function |
Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment.
|
| Subcellular Location |
Secreted.
|
| Top Pathways |
Focal adhesion, ECM-receptor interaction, PI3K-Akt signaling pathway
|