Gene Symbol | IBSP |
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Entrez Gene | 3381 |
Alt Symbol | BNSP, BSP, BSP-II, SP-II |
Species | Human |
Gene Type | protein-coding |
Description | integrin-binding sialoprotein |
Other Description | BSP II|bone sialoprotein 2|bone sialoprotein II|cell-binding sialoprotein |
Swissprots | P21815 |
Accessions | AAA60549 AAC37560 CAI61689 EAX05998 EAX05999 EAX06000 P21815 AA452255 AI751848 BC111920 AAI11921 BQ573754 DV462680 J05213 AAC95490 NM_004967 NP_004958 |
Function | Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment. |
Subcellular Location | Secreted. |
Top Pathways | Focal adhesion, ECM-receptor interaction, PI3K-Akt signaling pathway |
BSPII CRISPR/Cas9 KO Plasmid (h) - sc-402368 from Santa Cruz Biotechnology
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BSPII HDR Plasmid (h) - sc-402368-HDR from Santa Cruz Biotechnology
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BSPII Double Nickase Plasmid (h) - sc-402368-NIC from Santa Cruz Biotechnology
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BSPII Double Nickase Plasmid (h2) - sc-402368-NIC-2 from Santa Cruz Biotechnology
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BSPII CRISPR Activation Plasmid (h) - sc-402368-ACT from Santa Cruz Biotechnology
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BSPII CRISPR Activation Plasmid (h2) - sc-402368-ACT-2 from Santa Cruz Biotechnology
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BSPII Lentiviral Activation Particles (h) - sc-402368-LAC from Santa Cruz Biotechnology
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BSPII Lentiviral Activation Particles (h2) - sc-402368-LAC-2 from Santa Cruz Biotechnology
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BSPII siRNA (h) - sc-105128 from Santa Cruz Biotechnology
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BSPII shRNA Plasmid (h) - sc-105128-SH from Santa Cruz Biotechnology
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BSPII shRNA (h) Lentiviral Particles - sc-105128-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU002051 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10424 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10424 from Sigma-Aldrich
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IBSP siRNA (Human) - CRH2299 from Cohesion Biosciences
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IBSP - MBS8209779 from MyBioSource
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shRNA set against Human IBSP (NM_004967.3) - SHH316333 from Creative biogene
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shRNA set against Human IBSP(NM_004967.3) - SHL164352 from Creative biogene
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Human IBSP siRNA - orb262801 from Biorbyt
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IBSP shRNA Plasmid (Human) - CHH2299 from Cohesion Biosciences
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IBSP miRNA 3'UTR clone - MiUTR1H-04773 from Creative biogene
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