PARP2

Gene Symbol	PARP2
Entrez Gene	10038
Alt Symbol	ADPRT2, ADPRTL2, ADPRTL3, ARTD2, PARP-2, pADPRT-2
Species	Human
Gene Type	protein-coding
Description	poly (ADP-ribose) polymerase 2
Other Description	ADP-ribosyltransferase (NAD+; poly(ADP-ribose) polymerase)-like 2|ADP-ribosyltransferase diphtheria toxin-like 2|ADPRT-2|NAD(+) ADP-ribosyltransferase 2|hPARP-2|poly (ADP-ribose) polymerase family, member 2|poly (ADP-ribosyl) transferase-like 2|poly [ADP-ribose] polymerase 2|poly[ADP-ribose] synthase 2|poly[ADP-ribose] synthetase 2
Swissprots	Q9UMR4 Q9NUV2 Q9Y6C8 Q8TEU4 Q9UGN5
Accessions	AAL77437 CAC07442 EAW66476 EAW66477 EAW66478 Q9UGN5 AF085734 AAD29857 AJ236876 CAB41505 AJ236912 CAB65088 AK001980 BAA92017 AK290079 BAF82768 AK300971 BAG62594 BC172288 AAI72288 BU541261 DA354586 XM_005267247 XP_005267304 XM_011536311 XP_011534613 XM_011536312 XP_011534614 XR_943347 NM_001042618 NP_001036083 NM_005484 NP_005475
Function	Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Subcellular Location	Nucleus.
Tissue Specificity	Widely expressed, mainly in actively dividing tissues. The highest levels are in the brain, heart, pancreas, skeletal muscle and testis; also detected in kidney, liver, lung, placenta, ovary and spleen; levels are low in leukocytes, colon, small intestine, prostate and thymus.
Top Pathways	Base excision repair

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PARP2 peptide - ab105204 from Abcam Category Peptide

Human PARP2 protein fragment - ab140564 from Abcam Category Protein Source E. coli Species Human

Mouse PARP2 full length protein - ab168074 from Abcam Category Protein Source Baculovirus infected Sf21 cells Species Mouse

PARP2 Antibody Blocking Peptide - LS-E1532 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PARP2 Antibody Blocking Peptide - LS-E1599 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PARP2 Antibody Blocking Peptide - LS-E11944 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PARP2 Antibody Blocking Peptide - LS-E26030 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PARP2 Partial Recombinant Protein - H00010038-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human PARP2 Protein - NBP2-23339 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

PARP2 blocking peptide - GTX89417-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat

Human PARP2 protein - orb191397 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Source Escherichia Coli. Species Human

PARP2 Immunizing peptide - orb16780 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

PARP2 Blocking Peptide - 33R-5123 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PARP2 protein (His tag) - 80R-2707 from Fitzgerald Category Protein Prices $270.00 Sizes 100 µg Source E.coli

PARP2 Peptide - AC21-0858-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

PARP2 (233-583, His-tag) - AR50827PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

PARP2 (233-583, His-tag) - AR50827PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

PARP2 - H00010038-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

PARP2 - H00010038-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

PARP2, 233-583aa, Human, His tag, E.coli - 01-P2003 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

PARP2 Peptide - 46-134P from ProSci Category Peptide Species Human

PARP2 Human - ENPS-701 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human Poly (ADP-ribose) Polymerase 2, GST-tagged - PARP2-433H from Creative Biomart Category Protein Source Sf9 cell.

Recombinant Human PARP2, His-tagged - PARP2-27635TH from Creative Biomart Category Protein Source E. coli

Recombinant Human PARP2, His-tagged - PARP2-7559H from Creative Biomart Category Protein Source E. coli Species Human

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